Nozzle Liquid Storage Portion Prevents Overapplication

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Solution Overview

Problem

In immunochromatographic measurements, excessive liquid samples can lead to reduced sensitivity due to the liquid sample sliding on the chromatographic carrier instead of flowing, causing defects like false negatives, especially when manual addition results in overapplication.

Innovation Solution

A nozzle with a liquid storage portion that prevents excessive liquid from being jetted, featuring a tubular portion and guide structures to manage liquid flow, made from hydrophilic materials for improved wettability, ensuring a predetermined amount is stored and only the necessary amount is dispensed.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual addition of liquid sample is performed, then ease of operation is improved, but manufacturing precision deteriorates due to overapplication

Engineering Contradiction:
Improveease of operationVSAvoidmanufacturing precision
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The nozzle structure enables self-regulation of liquid flow through its internal geometry. The liquid storage portion and outlet configuration automatically control the dispensed amount without requiring external measurement or adjustment mechanisms, allowing manual operation while maintaining precision.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The invention changes the physical parameters of the nozzle structure, specifically creating a liquid storage portion with controlled volume and an outlet positioned at a specific height. These parameter changes ensure that only the necessary amount of liquid is dispensed, preventing overapplication while maintaining ease of manual operation.

Inventive Principle:
Principle #35Parameter changes

2Quantity of substance

If large amount of liquid sample is added, then quantity of substance is improved, but measurement precision deteriorates due to liquid sliding on chromatographic carrier

Engineering Contradiction:
Improvequantity of substanceVSAvoidmeasurement precision
Core Design Contradiction:
Quantity of substanceVSMeasurement precision

Solution Approach 1:

The invention changes the parameters of liquid delivery by controlling the exact volume stored in the nozzle's liquid storage portion and the height of the outlet. This ensures that only the necessary amount of liquid is dispensed onto the chromatographic carrier, preventing the liquid from sliding off while maintaining adequate quantity for measurement.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention replaces manual control mechanisms with a structurally determined liquid delivery system. The nozzle's internal geometry and outlet positioning automatically regulate liquid flow, substituting mechanical precision requirements with structural design that ensures proper liquid application without sliding.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Productivity

If all liquid from container is jetted, then productivity is improved, but measurement precision deteriorates due to excessive liquid application

Engineering Contradiction:
ImproveproductivityVSAvoidmeasurement precision
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The invention extracts only the necessary amount of liquid from the container through the nozzle's liquid storage portion. The outlet is positioned and sized to dispense only the required volume onto the chromatographic carrier, leaving excess liquid in the container rather than jetting all liquid, thus maintaining both productivity and measurement precision.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The invention changes the liquid delivery parameters by designing a liquid storage portion with specific volume capacity and an outlet at a controlled height. These parameter changes ensure that only the necessary amount of liquid is jetted onto the carrier per operation, maintaining productivity while preventing excessive liquid application that would compromise measurement precision.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This design effectively suppresses the reduction in sensitivity by ensuring the correct amount of liquid is applied to the chromatographic carrier, reducing losses and enhancing measurement accuracy.

Implementation Method 1

made from hydrophilic materials for improved wettability

Methodology Applied
Scientific EffectWetting: Wetting

Data Source

PatentUS11318484B2Nozzle and dispensing container
Publication Date: 2022.05.03 FUJIFILM CORP
  • US11318484B2 patent drawing
  • US11318484B2 patent drawing
  • US11318484B2 patent drawing

AI summary

A nozzle includes a mounting opening that is to be connected to an opening portion of a container, an outlet that jets liquid stored in the container, a side face that connects the mounting opening to the outlet, and a liquid storage portion that stores a part of the liquid stored in the container in the nozzle without jetting a part of the liquid from the outlet in a case where the liquid is to be jetted from the dispensing container, that is, in a case where the outlet faces downward in the direction of gravity.