Inbred Corn Line NPDC5592 Breeding Efficiency

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Solution Overview

Problem

Corn breeding faces challenges in producing high-yielding, agronomically sound plants that are uniformly adapted across different regions of the Corn Belt, as existing methods struggle to combine desired traits like yield, disease resistance, and adaptability to varying soil types and environments, often requiring extensive breeding and multiple backcrossing events.

Innovation Solution

The development of the inbred corn line NPDC5592, which includes specific genetic traits and transgenic genes for traits like male sterility, herbicide resistance, and modified starch, allows for the production of hybrid seeds with enhanced vigor and adaptability, using methods such as marker-assisted breeding to introduce targeted traits and reduce the number of backcrossing events.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If traditional corn breeding methods are used to combine desired traits, then trait diversity can be achieved, but the breeding process requires extensive time and multiple backcrossing events

Engineering Contradiction:
Improvetrait diversityVSAvoidbreeding time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The patent employs molecular markers as intermediary tools to track and select for desired traits during breeding. These markers serve as proxies for target genes, allowing breeders to identify and select plants carrying specific traits without waiting for phenotypic expression, thereby accelerating the breeding process and reducing the number of backcrossing events required

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces traditional mechanical/visual selection methods with molecular marker-based selection. Instead of relying on phenotypic observation and manual selection processes, the invention uses DNA analysis to identify and select plants with desired traits, substituting biochemical analysis for mechanical breeding approaches and significantly reducing breeding time

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Stability of the object's composition

If inbred lines are produced through extended self-pollination, then homozygosity and uniformity are achieved, but plant vigor decreases

Engineering Contradiction:
ImprovehomozygosityVSAvoidplant vigor
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent applies partial inbreeding strategies where self-pollination is used for a limited number of generations just enough to establish homozygosity at marker loci, rather than continuing extended self-pollination until complete homozygosity is achieved across all loci. This partial application of inbreeding maintains sufficient vigor while achieving the necessary genetic uniformity for breeding programs

Inventive Principle:
Principle #16Partial or excessive action

3Reliability

If detasseling is performed to produce hybrid seed, then cross-pollination control is improved, but production complexity and labor requirements increase

Engineering Contradiction:
Improvecross-pollination controlVSAvoidproduction complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent introduces molecular markers as intermediary indicators to track inheritance patterns and verify cross-pollination success. These markers serve as detectable signals that confirm whether desired traits have been inherited, reducing the need for complex mechanical controls like detasseling while maintaining reliable cross-pollination management

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS8530728B1Inbred corn line NPDC5592
Publication Date: 2013.09.10 SYNGENTA CROP PROTECITON AG

AI summary

Basically, this invention provides for an inbred corn line designated NPDC5592, methods for producing a corn plant by crossing plants of the inbred line NPDC5592, with plants of another corn plant. The invention relates to the various parts of inbred NPDC5592, including culturable cells. This invention also relates to methods for introducing transgenic transgenes into inbred corn line NPDC5592, and plants produced by said methods.