NPFA6896 Maize Inbred Plant Breeding

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Solution Overview

Problem

Corn breeding faces challenges in producing high-yielding, agronomically sound plants that are uniformly adapted across the U.S. Corn Belt, as regional growing conditions and specific issues like Gray Leaf Spot infection, cool temperatures, and soil pH levels require region-specific traits, and existing methods struggle to introduce desired traits efficiently into inbred lines.

Innovation Solution

The development of the maize inbred plant NPFA6896, which includes a mutant or transgenic gene conferring traits such as herbicide resistance, insect resistance, and disease resistance, and a method for introducing desired heritable traits through crossing, backcrossing, and selection processes to produce hybrid seeds with improved characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If traditional breeding methods are used to develop maize inbreds, then the breeding process is simpler and more straightforward, but the ability to introduce desired traits (herbicide resistance, insect resistance, disease resistance) efficiently is limited

Engineering Contradiction:
Improvebreeding process simplicityVSAvoidtrait introduction efficiency
Core Design Contradiction:
Ease of manufactureVSProductivity

Solution Approach 1:

The patent uses transgenic technology as an intermediary method to transfer desired traits between maize lines. Instead of relying solely on traditional slow breeding methods, genetic material conferring herbicide resistance, insect resistance, or disease resistance is directly introduced through transformation techniques, then stabilized through controlled backcrossing. This intermediary approach bridges the gap between simple traditional breeding and complex trait introduction needs.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Stability of the object's composition

If inbred lines are used for hybrid production, then uniformity and reproducibility of hybrid seed are improved, but the vigor and seed yield of the inbred plants themselves decrease

Engineering Contradiction:
Improvehybrid seed uniformityVSAvoidinbred plant vigor and seed yield
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The patent employs dynamic breeding strategies where inbred lines are continuously improved through recurrent selection and backcrossing with elite lines. Rather than treating inbreds as static, fixed lines, the program dynamically updates and refreshes the inbred genetic base by repeatedly crossing with superior sources and selecting for both vigor and desired traits. This dynamic approach maintains inbred uniformity for hybrid production while progressively improving inbred plant performance.

Inventive Principle:
Principle #15Dynamics

3Adaptability or versatility

If maize breeding targets regional adaptation to specific conditions (Gray Leaf Spot, cool temperatures, soil pH), then performance in those specific regions is improved, but the complexity of the breeding program increases

Engineering Contradiction:
Improveregional adaptationVSAvoidbreeding program complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The breeding program is segmented into distinct regional breeding streams, each focused on specific environmental challenges (e.g., one stream for Gray Leaf Spot resistance, another for cool temperature adaptation, another for soil pH tolerance). Each segment develops specialized inbred lines and hybrids optimized for its target region. This segmentation allows parallel development of multiple adapted lines without creating a single overly complex program, as each segment can be managed independently with its own selection criteria and breeding population.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS8481825B1Variety corn line NPFA6896
Publication Date: 2013.07.09 SYNGENTA CROP PROTECITON AG

AI summary

The present invention provides an inbred corn line designated NPFX6896, methods for producing a corn plant by crossing plants of the inbred line NPFX6896 with plants of another corn plant. The invention further encompasses all parts of inbred corn line NPFX6896, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line NPFX6896, and plants produced according to these methods.