Inbred Corn Line NPID2568 Marker-Assisted Breeding

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Solution Overview

Problem

Corn breeding faces challenges in producing high-yielding, agronomically sound plants that are uniformly adapted across different regions of the Corn Belt, as existing methods struggle to combine desired traits like yield, disease resistance, and adaptability to varying soil types and environments, often requiring extensive breeding and multiple backcrossing events.

Innovation Solution

The development of the inbred corn line NPID2568, which allows for the production of hybrid seeds and plants with specific traits such as male sterility, herbicide resistance, and disease resistance, using methods like marker-assisted breeding to introduce targeted traits and reduce the number of backcrossing events, and employing genetic male sterility systems to avoid detasseling.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If traditional corn breeding methods are used to combine desired traits, then trait diversity can be achieved, but the breeding process requires extensive backcrossing events and multiple generations, increasing time and complexity

Engineering Contradiction:
Improvetrait diversityVSAvoidbreeding time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The patent replaces traditional mechanical breeding methods (manual cross-pollination and selection over multiple generations) with molecular marker-based selection. Specific DNA markers are used to identify and select plants carrying desired traits, allowing breeders to achieve the same trait combination in fewer generations without relying on time-consuming phenotypic selection and backcrossing

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces molecular markers as intermediaries between genotype and phenotype selection. These markers serve as proxies for desired traits, enabling indirect selection of plants carrying specific genes or trait combinations. This intermediary system accelerates the breeding process by allowing selection at the DNA level rather than waiting for trait expression

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If traditional corn breeding methods are used to combine desired traits, then trait diversity can be achieved, but the breeding process complexity increases with multiple backcrossing events

Engineering Contradiction:
Improvetrait diversityVSAvoidbreeding process complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent replaces complex mechanical breeding procedures (multiple rounds of crossing, detasseling, and phenotypic selection) with a simplified molecular marker-based selection system. DNA extraction and marker analysis replace numerous manual操作步骤, reducing procedural complexity while maintaining trait diversity

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the selection parameter from phenotypic observation to genotypic analysis. By using molecular markers to detect specific DNA sequences associated with desired traits, the breeding process shifts from selecting based on physical characteristics to selecting based on genetic composition, simplifying the overall process

Inventive Principle:
Principle #35Parameter changes

3Reliability

If detasseling is used to produce hybrid seed, then male sterility can be achieved, but labor requirements and production complexity increase

Engineering Contradiction:
Improvemale sterilityVSAvoidhybrid seed production ease
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent replaces mechanical detasseling with genetic male sterility systems controlled by specific genes or cytoplasmic factors. Plants with these genetic characteristics naturally fail to produce functional pollen, eliminating the need for manual or mechanical removal of tassels while maintaining reliable male sterility for hybrid seed production

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS8203052B1Inbred corn line NPID2568
Publication Date: 2012.06.19 SYNGENTA CROP PROTECITON AG

AI summary

Basically, this invention provides for an inbred corn line designated NPID2568, methods for producing a corn plant by crossing plants of the inbred line NPID2568 with plants of another corn plant. The invention relates to the various parts of inbred NPID2568 including culturable cells. This invention also relates to methods for introducing transgenic transgenes into inbred corn line NPID2568 and plants produced by said methods.