Inbred Corn Line NPID4466 for Hybrid Seed Production

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Solution Overview

Problem

Corn breeding faces challenges in producing high-yielding, agronomically sound plants that are uniformly adapted across different regions of the Corn Belt, as existing inbred lines often require specific traits to overcome regional growing issues and are difficult to develop due to complex genetic systems and multi-genetic traits.

Innovation Solution

The development of the inbred corn line NPID4466, which is homozygous and self-pollinated to ensure uniformity and stability, combined with methods for introducing targeted traits using marker-assisted breeding and transgenic genes to enhance traits like disease resistance, herbicide resistance, and modified starch, allowing for the production of hybrid seeds with improved vigor and yield.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If inbred lines are developed through extended self-pollination to achieve homozygosity and uniformity, then genetic stability and reproducibility of hybrid seed are improved, but plant vigor and seed yield decrease

Engineering Contradiction:
Improvegenetic uniformityVSAvoidseed yield
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The breeding program segments the development process into distinct phases: creating highly homozygous inbred lines for genetic stability, then crossing them to produce F1 hybrids for vigor and yield. This segmentation allows each phase to optimize for its specific goal without compromise.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system dynamically transitions between homozygous inbred stages (for stability) and heterozygous hybrid stages (for productivity). The inbreds serve as stable genetic reservoirs that are periodically crossed to generate vigorous hybrid progeny, creating a cyclical breeding system that balances both requirements.

Inventive Principle:
Principle #15Dynamics

2Reliability

If existing inbred lines are used to produce hybrids, then regional adaptation can be achieved, but broader regional adaptability across the Corn Belt is limited

Engineering Contradiction:
Improveregional adaptationVSAvoidbroader regional adaptability
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

NPID4466 is designed as a universal inbred line that functions effectively across multiple regions of the Corn Belt. Through selective breeding and trait incorporation, it achieves multi-regional adaptability while maintaining the ability to be crossed with various partner inbreds for specific regional optimizations.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The inbred line incorporates a composite genetic makeup combining multiple desirable traits from different parental lines, including disease resistance, abiotic stress tolerance, and yield components. This genetic composite enables broad adaptability across diverse environmental conditions throughout the Corn Belt.

Inventive Principle:
Principle #40Composite materials

3Reliability

If complex genetic systems and multi-genetic traits are addressed in breeding, then agronomic soundness is improved, but breeding difficulty and time increase

Engineering Contradiction:
Improveagronomic soundnessVSAvoidbreeding time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The breeding program performs preliminary actions by pre-selecting and pre-combining multiple genetic traits into the NPID4466 inbred line before hybrid deployment. Disease resistance, stress tolerance, and yield traits are integrated in advance, reducing the need for further complex manipulation and accelerating the path to commercialization.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS8017843B1Inbred corn line NPID4466
Publication Date: 2011.09.13 SYNGENTA CROP PROTECITON AG

AI summary

Basically, this invention provides for an inbred corn line designated NPID4466, methods for producing a corn plant by crossing plants of the inbred line NPID4466 with plants of another corn plant. The invention relates to the various parts of inbred NPID4466 including culturable cells. This invention also relates to methods for introducing transgenic transgenes into inbred corn line NPID4466 and plants produced by said methods.