NSAID and Antihistamine Composition for Cold Symptom Inhibition
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Solution Overview
Problem
There is a need for an effective and accessible method to manage the symptoms of the common cold, as current prevention methods are inadequate and treatments only address symptoms after they appear.
Innovation Solution
A pharmaceutical composition comprising a non-steroidal anti-inflammatory drug (NSAID) and a co-agent such as fexofenadine, administered either before or at the onset of common cold symptoms to inhibit their occurrence or reduce their severity and duration.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If NSAIDs are administered to reduce common cold symptoms, then symptom severity is reduced, but adverse gastrointestinal effects increase
Solution Approach 1:
The patent combines NSAID with co-agents (antihistamines, analgesics, or decongestants) into a single pharmaceutical composition. This merging of multiple active ingredients addresses multiple symptoms simultaneously while the co-agents may mitigate gastrointestinal side effects of the NSAID component.
Solution Approach 2:
The invention creates a composite pharmaceutical formulation containing NSAID plus at least one co-agent from specified classes. This composite approach allows the therapeutic benefits of NSAID for pain and inflammation while the co-agents provide additional symptom relief and potentially reduce adverse effects.
2Ease of operation
If treatments are administered after symptom appearance, then symptom relief is provided, but prevention of symptom occurrence is not achieved
Solution Approach 1:
The patent enables administration of the pharmaceutical composition at the first sign of cold symptoms or even before symptom onset. This preliminary action approach allows the medication to work preventively or at the very early stage, potentially reducing the overall severity and duration before full symptom development occurs.
3Device complexity
If single-ingredient medications are used, then simplicity is maintained, but comprehensive symptom coverage is limited
Solution Approach 1:
The pharmaceutical composition is designed with multi-functionality to address various common cold symptoms simultaneously. The NSAID component handles pain and inflammation, while the co-agents (antihistamines for congestion, decongestants for nasal symptoms, or analgesics for body aches) provide additional targeted relief, making the single formulation universally applicable to multiple symptom types.
Data Source
AI summary
The present invention relates to a method of reducing or preventing the symptoms associated with the common cold. The method comprises administering to a subject an effective amount of a pharmaceutical composition before presenting with at least one symptom of the common cold. The pharmaceutical composition comprises a non-steroidal anti-inflammatory drug and a co-agent selected from the group consisting of: fexofenadine, ketotifen, desloratadine, salts thereof, and combinations thereof.