NT-PB Feed Additive for ATP Utilization Under Low-Energy Diets
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing animal diets with low energy levels face challenges in maximizing ATP utilization by animal muscle cells, leading to inefficient energy use and impaired growth performance.
Innovation Solution
A feed additive composed of guanidinoacetic acid, methionine, betaine, vitamin E, vitamin B12, vitamin B6, folic acid, L-ascorbic acid, L-carnitine, yeast selenium, and stearic acid, formulated to enhance ATP utilization by coating the pellets with stearic acid to protect the active ingredients and ensure they reach the small intestine intact, thereby improving energy reserves and muscle deposition.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Loss of energy
If low energy level diet is used, then cost is reduced, but ATP utilization rate decreases and growth performance is impaired
Solution Approach 1:
The patent introduces creatine phosphate as an intermediary energy storage substance in muscle cells. This mediator bridges the gap between limited dietary energy intake and high ATP demand, allowing cells to store energy temporarily and release it when needed, thereby improving ATP utilization rate while maintaining growth performance under low energy diet conditions
Solution Approach 2:
The patent modifies the energy metabolism parameters by increasing creatine phosphate content in muscle cells through dietary supplementation. This parameter change enables the cell to store more energy in the creatine phosphate pool, which can then be converted to ATP on demand, effectively improving energy utilization efficiency without requiring higher dietary energy levels
2Quantity of substance
If creatine phosphate is increased in muscle cells, then energy reserves are improved, but the complexity of feed formulation increases
Solution Approach 1:
The patent extracts and isolates creatine phosphate as a specific functional ingredient from complex energy metabolism systems. By identifying and separating this key energy storage substance, the formulation can focus on adding creatine phosphate directly rather than trying to manipulate the entire complex energy metabolism pathway, thereby reducing formulation complexity while improving energy reserves
Solution Approach 2:
The patent makes creatine phosphate a multi-functional ingredient that serves multiple purposes: it acts as an energy storage substance, an ATP regeneration substrate, and a muscle performance enhancer. This multi-functionality allows a single ingredient to address multiple energy-related needs, simplifying the overall feed formulation while achieving comprehensive energy improvement
Data Source
AI summary
A preparation method (NT-PB) and application for improving ATP utilization rate of animal muscle cells which includes the following components: guanidinoacetic acid, methionine, betaine, vitamin E, vitamin B12, vitamin B6, folic acid, L-ascorbic acid, L-carnitine, yeast selenium and stearic acid. The method supplements exogenous creatine synthetic raw materials for the animal body, and improves the efficiency of converting guanidinoacetic acid into creatine in the animal body, significantly increases the creatine level in the animal body, and improves the animal body's ability to function at a lower nutritional level (low energy, Under the conditions of low protein), the efficiency of ATP utilization can be reduced, and nutrients converted into energy and consumed, thereby significantly improving animal growth performance and slaughter performance. The raw materials of the invention are all nutritional additives, will not produce residues, are green and safe, meet the urgent needs of the rapid development of antibiotic-free animal husbandry.