Nucleic Acid Sequence Security via Composite Data Masking
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing methods for analyzing nucleic acid sequences expose sensitive genetic information to analysts, increasing the risk of information exposure and security vulnerabilities.
Innovation Solution
A nucleic acid sequence security method using a sparse matrix to create composites with target and disguising elements, allowing analysis without exposing the original sequence, and transmitting unit-based interpretation results to maintain security and minimize calculation load.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If nucleic acid sequence information is transmitted to an analyst for analysis, then analysis capability is improved, but security risk increases due to exposure of sensitive genetic information
Solution Approach 1:
The nucleic acid sequence is divided into multiple segments, and only specific segments containing target elements are transmitted to the analyst for analysis. This segmentation allows the analyst to perform analysis on partial information without accessing the complete sequence, thereby maintaining security while enabling analysis capability.
Solution Approach 2:
A third party system (the nucleic acid sequence security method) acts as an intermediary between the information holder and the analyst. This intermediary creates composite data structures that contain both target elements and dummy elements, allowing analysis to proceed on masked data without exposing the original sequence to the analyst.
2Measurement precision
If complete nucleic acid sequence is provided to analyst, then analysis accuracy is improved, but information exposure risk increases
Solution Approach 1:
Different parts of the transmitted data have different qualities: target elements maintain their analytical value for accurate results, while dummy elements provide structural filler that masks the actual sequence information. This local differentiation allows the analyst to obtain accurate analysis on target regions without exposing the complete sequence.
Solution Approach 2:
Instead of transmitting the original nucleic acid sequence, a copied and modified version is created where target elements are preserved but dummy elements are inserted. This copy maintains sufficient information for accurate analysis while altering the data structure to prevent complete sequence exposure.
3Object-affected harmful factors
If security measures are strengthened to protect nucleic acid sequence, then security risk is reduced, but calculation load on analyst increases
Solution Approach 1:
Only partial action is performed by transmitting only the necessary target elements rather than the complete sequence. This partial transmission reduces the data volume and calculation load on the analyst while maintaining sufficient information for accurate analysis, and simultaneously enhances security by limiting exposure.
4Object-affected harmful factors
If nucleic acid sequence is masked with dummy elements, then security is improved, but data processing complexity increases
Solution Approach 1:
The data structure parameters are changed by inserting dummy elements alongside target elements in a controlled manner. This parameter modification maintains the overall data structure for ease of processing while adding security through the presence of masked elements. The systematic approach to parameter change prevents excessive processing complexity.
Data Source
AI summary
A nucleic acid sequence security method comprises the steps of: (a) creating a plurality of composites each comprising at least one of target elements derived from a nucleic acid sequence of an analysis requester or disguising elements identical to or different from the target elements; and (b) providing the created plurality of composites to an analyst.