Nucleic Acid Encryption via Secret Codebook Mapping
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Solution Overview
Problem
Existing technologies do not adequately preserve the privacy of nucleic acid information, which has significant implications for individual identity and related persons, as genetic sequencing becomes more common and cost-effective.
Innovation Solution
A method and apparatus for physically encrypting nucleic acid using a computing device to generate a nucleic acid codebook based on a secret input by the subject, correlating code patterns and keys to values, and a manufacturing device to encrypt the nucleic acid sample using this codebook, producing an encrypted sample.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Loss of information
If nucleic acid sequencing is performed to obtain genetic information, then useful genetic data is obtained, but privacy of individual identity and related persons is compromised
Solution Approach 1:
The patent segments genetic information into two distinct forms: encrypted nucleic acid sequences that preserve privacy, and decoded information that provides useful genetic data. The encryption system separates the storage of genetic data in encrypted form from the temporary decoding process, allowing both privacy preservation and data utility to coexist through spatial and temporal segmentation of information states.
Solution Approach 2:
The patent introduces an intermediary encryption system that acts as a mediator between the raw nucleic acid sample and the final genetic information. The encrypted nucleic acid sequence serves as an intermediary representation that maintains the structure and utility of genetic data while obscuring the actual identity information, allowing downstream analysis without direct exposure of sensitive personal data.
2Loss of information
If genetic information is encrypted to protect privacy, then privacy is preserved, but accessibility and usability of the data is reduced
Solution Approach 1:
The patent applies preliminary encryption action to nucleic acid sequences before they are stored or shared. By pre-encrypting the genetic information while maintaining its structural integrity, the system ensures that privacy protection is already in place before any data access or analysis occurs, eliminating the need for additional access controls while preserving usability through the reversible nature of the encryption.
Solution Approach 2:
The patent changes the parameter state of nucleic acid sequences from plaintext to encrypted form, transforming the data representation while preserving its functional properties. This parameter change allows the data to maintain its utility for genetic analysis while altering its form to provide privacy protection, enabling both easy accessibility and strong privacy protection simultaneously.
Data Source
AI summary
An apparatus for physically encrypting nucleic acid, wherein the apparatus include at least a computing device configured to receive a nucleic acid sample from a subject, input a secret defined by the subject, generate a nucleic acid codebook as a function of the secret, wherein the nucleic acid codebook include a code pattern and a plurality of nucleic acid keys correlates to a plurality of nucleic acid values, and at least a manufacturing device configured to encrypt a nucleic acid sample received from a subject as a function of the nucleic acid codebook, and output an encrypted nucleic acid sample.