Nucleic Acid Sample Processing Transfer Structure for Compact Testing

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Solution Overview

Problem

The volume of nucleic acid testing integrated machines is large due to the need for multiple modules and grippers to transfer consumables, requiring a significant operational space.

Innovation Solution

A to-be-tested object processing apparatus with a frame body, extraction mechanism, grabbing part, and transfer part that allows for vertical and horizontal movement of components, reducing space occupation by optimizing the transfer of extraction and amplification plates and consumables.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If multiple modules and grippers are used to transfer consumables between modules, then the nucleic acid testing integrated machine can perform extraction operations, but the volume of the apparatus increases significantly

Engineering Contradiction:
Improveextraction operation capabilityVSAvoidapparatus volume
Core Design Contradiction:
Adaptability or versatilityVSVolume of stationary object

Solution Approach 1:

The patent combines the gripper and transfer part into a single integrated structure. The gripper is movably arranged on the transfer part, allowing the transfer part to carry consumables between modules while the gripper performs picking and placing operations. This merging eliminates the need for separate transfer mechanisms for each module, significantly reducing the overall apparatus volume while maintaining extraction operation capability.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The transfer part is designed as a universal platform that can transport multiple types of consumables (extraction plates, amplification plates, reagent bottles) between different modules. The gripper can adapt to grasp different consumable types, making the transfer system multi-functional rather than requiring dedicated transfer mechanisms for each consumable type.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Ease of operation

If the operation area of the gripper is arranged sufficiently large to transfer consumables between modules, then the gripper can access all modules, but the space occupation and apparatus volume increase

Engineering Contradiction:
Improvegripper accessibilityVSAvoidoperation area
Core Design Contradiction:
Ease of operationVSArea of stationary object

Solution Approach 1:

The gripper is designed with movable arrangement on the transfer part, allowing it to dynamically adjust its position and orientation when transferring different consumables. The gripper can rotate and translate relative to the transfer part, enabling it to access various modules and consumable types from a compact base position, thus maintaining ease of operation without requiring a large static operation area.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The gripper's movement is enabled in multiple dimensions through its movable arrangement on the transfer part. Instead of requiring a large two-dimensional operation area, the gripper utilizes vertical movement, rotation, and translation along the transfer part to access different modules, effectively using three-dimensional space to reduce the required footprint area.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Data Source

PatentEP4403924B1To-be-tested object processing apparatus and nucleic acid testing integrated machine with to-be-tested object processing apparatus
Publication Date: 2025.08.27 SHENZHEN NEW INDS BIOMEDICAL ENG CO LTD
  • EP4403924B1 patent drawingFigure 1
  • EP4403924B1 patent drawingFigure 2
  • EP4403924B1 patent drawingFigure 3

AI summary

The invention provides a to-be-tested object processing apparatus and a nucleic acid testing integrated machine with the to-be-tested object processing apparatus. The to-be-tested object processing apparatus includes: a frame (10), provided with a sample processing platform (11); an extraction mechanism (30), configured to extract an analyte; a grabbing part (40), movably arranged above the sample processing platform (11); a transfer part (50) being movably arranged on the sample processing platform (11), the transfer part (50) including an extraction plate transfer part (53), the extraction plate transfer part (53) being provided with a first transfer position, the grabbing part (40) being provided with a first grabbing position and a second grabbing position, and when the extraction plate transfer part (53) is located in the first transfer position, the grabbing part (40) being able to move between the first grabbing position and the second grabbing position; and a pipetting part (60), movably arranged above the sample processing platform (11), wherein the extraction plate transfer part (53) is further provided with a sample adding position, and when the extraction plate transfer part (53) is located in the sample adding position, the pipetting part (60) is further provided with a first pipetting position. The technical solution of the invention solves the problem that the volume of the nucleic acid testing integrated machine is large.