Nucleic Acid Information Storage Encryption

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Solution Overview

Problem

Current methods for storing and transmitting information using nucleic acids face challenges in providing effective encryption and decryption methodologies for secure information storage and retrieval, particularly in digital storage and transmission systems.

Innovation Solution

A method is developed to securely translate and encrypt information formats, such as text or images, into nucleic acid constructs by converting each character into triplet or quadruplet codons, generating a nucleic acid sequence that includes a lock region, a translation key region, and a message region, allowing for secure storage and transmission, and enabling decryption and translation back into the original format.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If digital storage and transmission methods are used, then information can be stored and transmitted efficiently, but security and susceptibility to compromise worsen

Engineering Contradiction:
Improveinformation storage efficiencyVSAvoidinformation security
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent replaces digital information storage systems with a biological nucleic acid-based system. Information is encoded into nucleic acid sequences using codon translation, where digital data is converted into biological molecules that can be stored and transmitted with enhanced security properties, fundamentally substituting the storage medium rather than just improving the digital system

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the fundamental parameter of information representation from digital bits to nucleic acid codons. By using triplet or quadruplet codons to represent characters, the system transforms information into a different chemical and physical domain, achieving both efficient storage and improved security through the inherent properties of nucleic acid molecules

Inventive Principle:
Principle #35Parameter changes

2Reliability

If nucleic acid constructs are used for information storage, then security is improved, but encryption and decryption complexity increases

Engineering Contradiction:
Improveinformation securityVSAvoidencryption methodology complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent segments the information storage system into distinct functional components: a lock region containing primer binding sites, a translation key region with codon assignments, and a message region with the encrypted information. This segmentation allows each component to be independently designed and optimized, simplifying the overall encryption methodology while maintaining security

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces a translation key as an intermediary element that mediates between the encrypted nucleic acid message and the original information. The translation key contains codon assignments that act as a bridge, allowing secure storage without requiring complex encryption algorithms, as the security relies on the biological translation process rather than mathematical cryptography

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If triplet or quadruplet codons are used to encrypt information, then the number of unique libraries increases, but the nucleic acid sequence length increases

Engineering Contradiction:
Improvenumber of unique librariesVSAvoidnucleic acid sequence length
Core Design Contradiction:
Adaptability or versatilityVSLength of moving object

Solution Approach 1:

The patent uses partial codon utilization by selecting specific triplet or quadruplet codons for the translation key rather than using all possible codons. This partial action approach generates sufficient uniqueness for security purposes (over 10^89 unique libraries with triplet codons) while avoiding the excessive sequence length that would result from using all 64 triplet codons or 256 quadruplet codons

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

The patent applies different codon strategies to different regions of the nucleic acid construct. The lock region uses standard primer binding sequences, the translation key region uses selected codons for character representation, and the message region uses the encrypted information. This local differentiation optimizes each region for its specific function while managing overall sequence length

Inventive Principle:
Principle #3Local quality

Data Source

PatentUS11854669B1Synthetic nucleic acids for information storage and transmission
Publication Date: 2023.12.26 NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA LLC
  • US11854669B1 patent drawing
  • US11854669B1 patent drawing
  • US11854669B1 patent drawing

AI summary

The present invention relates to method for storing and transmitting information by employing a nucleic acid construct. The nucleic acid construct can include a lock region; a translation key region that corresponds to the identity of a key; and a message region including a nucleic sequence that corresponds to an encrypted message.