Nutrient-Mediated Phytochemical Delivery Through Cell Membranes

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Solution Overview

Problem

Current methods fail to effectively deliver pharmacologically active phytochemicals across cell membranes for enhanced health benefits, as they often rely on inefficient or non-specific mechanisms.

Innovation Solution

A method involving the attachment of small molecule phytochemicals to nutrients that naturally pass through cell membranes, leveraging metabolic processes to ensure delivery and utilization within cells, supplemented with detoxifiers, prebiotics, and probiotics for enhanced activity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional methods are used to deliver pharmacologically active phytochemicals across cell membranes, then the delivery process can be simplified, but the delivery efficiency and specificity are insufficient

Engineering Contradiction:
Improvedelivery efficiencyVSAvoiddelivery mechanism complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent employs nutrients (such as amino acids, sugars, and lipids) as intermediary carriers to transport pharmacologically active phytochemicals across cell membranes. These nutrients serve as mediators that naturally facilitate membrane penetration while delivering the active compounds, thereby achieving efficient and specific delivery without requiring complex artificial transport systems.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention leverages the cell's own metabolic processes and natural nutrient transport mechanisms to deliver phytochemicals. By utilizing the cell's inherent ability to absorb and process nutrients, the system achieves self-service delivery where the cell's metabolic activity itself facilitates the transport of active compounds, eliminating the need for external complex delivery mechanisms.

Inventive Principle:
Principle #25Self-service

2Manufacturing precision

If non-specific delivery mechanisms are used, then the process is simpler, but the targeting precision and health benefits are reduced

Engineering Contradiction:
Improvedelivery targeting precisionVSAvoidprocess simplicity
Core Design Contradiction:
Manufacturing precisionVSEase of manufacture

Solution Approach 1:

The patent applies local quality by selecting specific nutrients that target particular cell types or metabolic pathways. Different nutrients can be used to deliver phytochemicals to specific tissues or cells based on their metabolic characteristics, achieving precise targeting while maintaining relatively simple delivery processes through the natural specificity of nutrient absorption mechanisms.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach ensures targeted and efficient delivery of bioactive phytochemicals, enhancing health protection and benefits by utilizing natural metabolic pathways, providing a steady supply of active compounds and supporting cellular functions.

Implementation Method 1

the selective small molecule P and P active media attaches to a foodstuff that is brought through the cell membrane as part of the cell's normal metabolic activity

Methodology Applied
Scientific EffectMetabolic activity:

Data Source

PatentUS10806767B1Method and preparation for the delivery of selective small molecule phytochemical based and pharmacologically active media through a cell membrane to enhance food groups for health protection and benefits
Publication Date: 2020.10.20 SAHA ANUJ K
  • US10806767B1 patent drawing
  • US10806767B1 patent drawing
  • US10806767B1 patent drawing

AI summary

The method and preparation for the delivery of selective small molecule phytochemical based and pharmacologically active media through a cell membrane to enhance food groups for health protection and benefits is a method of selectively delivering a pharmacologically active small molecule phytochemical to specifically targeted cells within a body. The method comprises attaching the pharmacologically active small molecule phytochemical to a nutrient. The nutrient is selected such that the nutrient is selectively brought into the targeted cells as part of the metabolic process. The selected nutrient brings the pharmacologically active small molecule phytochemical through a cell membrane with the selected nutrient. The methodologies/process described in this application are referred to as the “Guru-Vishnu” process.