At-Home Nutritional Response Measurement Accuracy via ML Validation

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Solution Overview

Problem

At-home measurements of nutritional responses are often less accurate than those taken in clinical settings due to factors like contamination, user compliance, and lack of controlled conditions, limiting the ability to provide personalized dietary recommendations to individuals.

Innovation Solution

The use of computing devices and data accuracy services that combine multiple measurements from various sources, such as continuous glucose monitors, at-home blood tests, and wearable devices, along with machine learning mechanisms to adjust and validate test data, improves the accuracy of nutritional response measurements by correcting for errors and inconsistencies.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If measurements are taken in a clinical setting, then measurement precision is improved, but cost increases and accessibility decreases

Engineering Contradiction:
Improveaccuracy of nutritional response measurementsVSAvoidcost and accessibility of measurements
Core Design Contradiction:
Measurement precisionVSEase of manufacture

Solution Approach 1:

The patent creates a virtual replica of clinical-grade measurement conditions by using machine learning models trained on clinical data to process and validate at-home measurement data. This copying approach allows at-home devices to achieve clinical-level accuracy without requiring actual clinical infrastructure, thereby reducing cost and improving accessibility while maintaining measurement precision.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent introduces an intermediary layer of machine learning validation services that act as a bridge between at-home measurement devices and clinical-grade accuracy requirements. This intermediary validates at-home measurements by comparing them against clinical data patterns, enabling accurate nutritional response assessment without direct clinical involvement, thus reducing cost while maintaining precision.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of manufacture

If at-home measurements are used, then cost decreases and accessibility improves, but measurement precision deteriorates due to contamination and user compliance issues

Engineering Contradiction:
Improvecost and accessibility of measurementsVSAvoidaccuracy of nutritional response measurements
Core Design Contradiction:
Ease of manufactureVSMeasurement precision

Solution Approach 1:

The patent implements feedback mechanisms where machine learning models continuously learn from both at-home and clinical measurement data. The system provides feedback to users about proper measurement techniques and validates at-home measurements by comparing them against expected patterns derived from clinical data, thereby improving measurement precision while maintaining the cost and accessibility advantages of at-home testing.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent replaces the mechanical/physical control systems of clinical settings (trained staff, controlled environments, standardized procedures) with an information-based machine learning validation system. This substitution allows at-home measurements to achieve clinical-level accuracy by using computational methods to detect and correct errors related to contamination and user compliance, while maintaining the cost and accessibility benefits of at-home testing.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Measurement precision

If multiple measurements from various sources are combined, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improveaccuracy of nutritional response measurementsVSAvoidcomplexity of data integration system
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent merges multiple data sources (continuous glucose monitors, at-home blood tests, wearable devices, clinical measurements) into a unified machine learning validation framework. By combining these diverse measurement sources and processing them through a single integrated learning system, the patent achieves improved measurement precision while managing complexity through unified data processing rather than separate analysis systems.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS11348479B2Accuracy of measuring nutritional responses in a non-clinical setting
Publication Date: 2022.05.31 ZOE GLOBAL LTD
  • US11348479B2 patent drawing
  • US11348479B2 patent drawing
  • US11348479B2 patent drawing

AI summary

Techniques are disclosed herein for improving the accuracy of nutritional responses measured in a non-clinical setting. Using the technologies described herein, different techniques can be utilized to improve the accuracy of test data associated with one or more “at home” tests. In some examples, more than one test is utilized to improve the accuracy of test data associated with a particular biomarker. In other examples, a data accuracy service can programmatically analyze data received from an individual and determine whether the data is accurate. In some examples, a computing device is utilized to assist in determining what food item(s) are consumed, as well as determine whether a test protocol was followed.