Occlusion Device with Segmented Nitinol Frame

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Solution Overview

Problem

Existing occlusion devices for bodily passages face limitations due to bulkiness, reliance on thrombosis for occlusion, and reduced effectiveness in patients with clotting disorders, such as those undergoing anti-coagulant therapy.

Innovation Solution

The development of occlusion devices featuring a disc-shaped support frame with a crossbar and a covering, designed to provide a mechanical blockage without relying on thrombosis, utilizing a flexible disc-shaped member and crossbar structure made from biocompatible materials like Nitinol and cobalt chromium, with a covering that ensures continuous contact to block fluid flow effectively.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If complex multi-filament frame structures are used to achieve occlusion, then occlusion effectiveness is improved, but device bulk and profile increase limiting use to larger passages

Engineering Contradiction:
Improveocclusion effectivenessVSAvoiddevice bulk
Core Design Contradiction:
ReliabilityVSVolume of moving object

Solution Approach 1:

The frame structure is divided into multiple discrete elements (first frame element, second frame element, third frame element) that are interconnected. This segmentation allows each element to be optimized independently for strength while reducing overall material usage and device bulk compared to a solid multi-filament structure.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The frame elements are constructed as thin-walled tubular structures rather than solid multi-filament bundles. This thin-film approach maintains structural integrity and occlusion effectiveness while significantly reducing device bulk and profile, enabling deployment in smaller bodily passages.

Inventive Principle:
Principle #30Flexible shells and thin films

2Reliability

If thrombosis-based occlusion mechanism is used, then occlusion is achieved, but effectiveness is reduced in patients with clotting disorders and thrombus may be reabsorbed over time

Engineering Contradiction:
Improveocclusion effectivenessVSAvoidapplicability to patients with clotting disorders
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The invention replaces the biochemical thrombosis-based occlusion mechanism with a purely mechanical blockage system. The frame structure physically obstructs fluid flow through its geometric configuration, providing reliable occlusion that is independent of the patient's clotting ability and not subject to thrombus reabsorption.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Volume of moving object

If reduced device bulk is achieved for easier delivery, then deliverability to smaller vessels is improved, but structural strength may be compromised

Engineering Contradiction:
Improvedevice bulkVSAvoidframe structural strength
Core Design Contradiction:
Volume of moving objectVSStrength

Solution Approach 1:

The frame elements are constructed from elastic memory materials (such as Nitinol) that provide exceptional strength-to-weight ratio. This composite approach combines the flexibility and low bulk of thin-walled structures with the high structural strength of shape memory alloys, enabling small device profile without compromising occlusion effectiveness.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The frame elements utilize elastic memory properties to dynamically adapt their configuration. During delivery, the compressed low-bulk configuration is maintained, and upon deployment, the elastic memory effect restores the frame to its high-strength occlusive configuration, providing both reduced bulk and maintained strength.

Inventive Principle:
Principle #15Dynamics

Data Source

PatentEP2627265B8Occlusion device for blocking fluid flow through bodily passages
Publication Date: 2019.02.20 COOK MEDICAL TECHNOLOGIES LLC

AI summary

An occlusion device has a covering attached to a support frame that includes a disc-shaped member and a crossbar that extends across a central opening defined by the disc-shaped member. The occlusion device has a first, or deployed, configuration in which the crossbar defines a curve that extends from the disc-shaped member, and a second, or resting, configuration in which the discshaped member and the crossbar lie substantially in a single plane. Each of the disc-shaped member and the crossbar include a core wire that extends through a lumen of a coil multiple times.