OCT-A Decorrelation Tail Artifact Correction

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Solution Overview

Problem

Current methods for correcting decorrelation tail artifacts in OCT angiography are limited by reliance on slab definitions, which can lead to errors in segmentation, masking of real signals, and increased processing time, and do not allow for automated optimization or visualization of vascular pathologies.

Innovation Solution

A method that corrects decorrelation tail artifacts by axially moving a sliding window through the OCT-A volumetric data, using previously corrected information from a reference subvolume to update the target subvolume, independent of slab definitions, allowing for automated optimization and visualization of pathologies.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If slab-based correction methods are used to remove decorrelation tail artifacts, then artifacts in specific layers can be reduced, but segmentation errors occur and real signals may be masked

Engineering Contradiction:
Improvedecorrelation tail artifactsVSAvoidsegmentation accuracy
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent divides the OCT-A volume into multiple thin axial subvolumes (slabs) that are processed sequentially from superficial to deep layers. Each subvolume is corrected independently using information from previously corrected subvolumes, allowing precise artifact removal without the segmentation errors associated with traditional methods that require predefined layer boundaries.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The correction process proceeds axially from superficial to deep layers, using previously corrected subvolumes as reference for correcting subsequent subvolumes. This preliminary action ensures that when correcting a given subvolume, the artifacts from superficial vessels have already been removed from the reference data, preventing mask errors and preserving real signals.

Inventive Principle:
Principle #10Preliminary action

2Object-affected harmful factors

If traditional slab-based correction is applied repeatedly for different slabs, then artifact correction can be achieved, but processing time increases significantly

Engineering Contradiction:
Improvedecorrelation tail artifactsVSAvoidprocessing time
Core Design Contradiction:
Object-affected harmful factorsVSLoss of time

Solution Approach 1:

The patent implements a continuous axial sweep through the entire OCT-A volume, correcting subvolumes sequentially in a single pass. Each corrected subvolume becomes part of the reference for subsequent corrections, eliminating the need for repeated correction algorithms and reducing processing time while maintaining continuous artifact removal throughout the volume.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

By performing the correction axially from superficial to deep layers in a single continuous process, the patent ensures that each subvolume is corrected once using already-corrected reference data. This preliminary correction approach prevents the need for iterative or repeated corrections, significantly reducing processing time.

Inventive Principle:
Principle #10Preliminary action

3Measurement precision

If high density sampling is used to achieve high resolution en face visualization, then image quality improves, but scan time increases by an order of magnitude

Engineering Contradiction:
Improveen face visualization resolutionVSAvoidscan time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent segments the 3D OCT-A volume into multiple 2D en face subvolumes at different axial depths and processes them sequentially. This allows high-resolution visualization of each layer independently while using the segmented approach to reduce the overall scan time required to acquire and process the complete volumetric data set.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system acquires OCT-A data in periodic B-scans at different time points and processes these periodically acquired subvolumes through the correction algorithm. This periodic acquisition method enables high-resolution en face visualization of multiple layers while managing scan time through efficient temporal sampling.

Inventive Principle:
Principle #19Periodic action

Data Source

PatentUS10441164B1Correction of decorrelation tail artifacts in a whole OCT-A volume
Publication Date: 2019.10.15 CARL ZEISS MEDITEC INC
  • US10441164B1 patent drawing
  • US10441164B1 patent drawing
  • US10441164B1 patent drawing

AI summary

A method and system for correction of decorrelation tail artifacts in optical coherence tomography (OCT) angiography volumetric data defines a movable target subvolume within the OCT-A volumetric data. The target subvolume is axially moveable within the OCT-A volumetric data in discrete axial steps. At each axial step, a reference subvolume corresponding to a depth location in the OCT A volumetric data is defined axially offset from the target subvolume. The reference subvolume may be defined within the OCT A volumetric data, or defined within a different (previously corrected) OCT-A volume. Irrespective, corrected OCT-A data that corrects for decorrelation tail artifacts in the target subvolume is defined using information in the reference subvolume and information in the target subvolume.