Ocular Biometry With Trial Lens Stabilization for Accurate IOL Selection

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Solution Overview

Problem

Existing ocular biometry methods, particularly for combined phaco-vit procedures, face inaccuracies due to retinal conditions like retinal detachment, vitreous hemorrhage, and cataracts, leading to improper IOL selection and poor post-surgical vision correction.

Innovation Solution

A method and apparatus involving phacoemulsification, vitrectomy, and placement of a temporary trial lens in the lens capsule to stabilize the capsule shape, allowing accurate biometry using intraoperative OCT and aberrometry, considering infusion fluid refractive indices, to select and verify the IOL.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If ultrasound-based axial length measurements are performed, then measurements can be obtained in certain retinal conditions, but measurement precision deteriorates due to retinal detachment, vitreous hemorrhage, and other retinal conditions

Engineering Contradiction:
ImproveAbility to perform measurements in retinal conditionsVSAvoidAxial length measurement accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent performs vitrectomy and places a trial lens in the lens capsule before performing biometry measurements. This preliminary preparation stabilizes the optical path and lens capsule position, enabling accurate low coherence interferometry measurements to be performed intraoperatively after the retinal conditions are addressed but before IOL implantation.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent replaces ultrasound-based mechanical measurement with optical low coherence interferometry measurement. This substitution eliminates the acoustic impedance issues that plague ultrasound measurements in retinal conditions, providing superior measurement precision while still enabling measurements to be performed intraoperatively.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If low coherence interferometry is performed pre-operatively, then measurement precision improves, but reliability deteriorates when vitreous hemorrhage or retinal detachment is present

Engineering Contradiction:
ImproveAxial length measurement accuracyVSAvoidAbility to obtain measurements in retinal conditions
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent performs vitrectomy and places a trial lens in the lens capsule before performing biometry measurements. This preliminary preparation clears the visual path by removing vitreous hemorrhage and stabilizes the optical path, enabling reliable low coherence interferometry measurements to be performed intraoperatively after the retinal conditions are addressed.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent replaces pre-operative ultrasound measurement with intraoperative low coherence interferometry measurement. This substitution maintains the high precision of optical measurement while overcoming the reliability issues by performing measurements after vitrectomy clears the visual path and stabilizes the optical environment.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Productivity

If IOL is selected based on pre-operative measurements with retinal conditions, then IOL implantation can be performed, but manufacturing precision deteriorates resulting in refractive errors

Engineering Contradiction:
ImproveIOL implantation speedVSAvoidRefractive accuracy
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent performs vitrectomy and places a trial lens in the lens capsule before performing biometry measurements and selecting the IOL. This preliminary preparation ensures that measurements are taken under optimal conditions with the lens capsule stabilized and the visual path cleared, enabling accurate IOL selection that achieves the desired refractive target.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses intraoperative low coherence interferometry to obtain real-time biometry measurements after vitrectomy and trial lens placement. This feedback loop allows the surgical team to verify measurement accuracy, confirm IOL selection, and make adjustments if needed before final IOL implantation, ensuring refractive precision while maintaining surgical efficiency.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables precise IOL selection by stabilizing the lens capsule shape and accounting for retinal conditions, ensuring accurate refractive outcomes and improved post-surgical vision.

Implementation Method 1

axial length measurements of a patient's eye with retinal conditions... using low coherence interferometry

Methodology Applied
Scientific EffectLow coherence interferometry: Interference

Implementation Method 2

phacoemulsification cataract surgery in which the eye's internal lens is emulsified with an ultrasonic handpiece

Methodology Applied
Scientific EffectUltrasonic vibration: Ultrasonic Vibration

Data Source

PatentUS12350195B2Methods and apparatus for performing ocular biometry
Publication Date: 2025.07.08 ALCON INC
  • US12350195B2 patent drawing
  • US12350195B2 patent drawing
  • US12350195B2 patent drawing

AI summary

Certain embodiments provide a method of performing ocular biometry. The method includes performing phacoemulsification to emulsify and remove an internal lens of an eye. The method further includes performing vitrectomy to remove vitreous from the eye. The method also includes placing a trial in a lens capsule of the eye. The method further includes performing biometry with a first biometry system to provide measurements including at least one of an axial length of the eye, a curvature of a cornea of the eye, and toric axis. The method also includes removing the trial from the lens capsule.