Ocular Composition for Eyelid Cleansing and Antimicrobial Protection

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Solution Overview

Problem

Current eyelid cleansers often irritate sensitive eye tissue and fail to effectively prevent recurring bacterial infections associated with blepharitis and sties, as they are not specifically designed for ocular hygiene and lack adequate antimicrobial properties.

Innovation Solution

A composition comprising purified water, PEG-80 sorbitan laurate, sodium trideceth sulfate, PEG-150 distearate, sodium lauroamphoacetate, cocamidopropyl hydroxysultaine, sodium laureth-13 carboxylate, sodium chloride, polyhexamethylene biguanide, potassium sorbate, 1,2 hexanediol, and caprylyl glycol, which provides a non-irritating yet antimicrobial effect, controlling pH with surfactants to reduce irritation and enhance cleansing ability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If simple skin cleansers are used on eyelids, then cleansing ability is provided, but irritation occurs to sensitive eye tissue

Engineering Contradiction:
Improvecleansing abilityVSAvoidirritation to eye tissue
Core Design Contradiction:
Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

The patent modifies the chemical parameters of the cleanser by using mild surfactants with specific pH ranges (5.0-7.0) and incorporating buffering agents to maintain physiological compatibility. This resolves the contradiction by adjusting composition parameters to reduce irritation while preserving cleansing effectiveness.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention creates a composite formulation combining multiple gentle surfactants (amphoteric, nonionic, and anionic types) with buffering agents and moisturizing components. This composite approach allows the cleanser to maintain cleansing ability through synergistic surfactant action while the buffering system and additional ingredients mitigate irritation to sensitive ocular tissues.

Inventive Principle:
Principle #40Composite materials

2Ease of operation

If baby shampoo is diluted and used for eyelid cleansing, then some cleansing effect is achieved, but adequate antimicrobial protection is not provided

Engineering Contradiction:
Improvecleansing effectVSAvoidantimicrobial protection
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent merges cleansing functionality with antimicrobial protection by integrating mild surfactants and buffering agents into a single formulation. This combination therapy approach ensures that one product delivers both gentle cleansing and reliable antimicrobial action, eliminating the need for separate treatments and addressing both aspects simultaneously.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a multi-functional eyelid cleanser that performs both cleansing and antimicrobial protection in one product. The formulation is designed to handle multiple functions - removing debris and oil while providing sustained antimicrobial activity - thereby resolving the contradiction between ease of use and reliable protection.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Stability of the object's composition

If traditional pH adjusters are used in eyelid cleansers, then pH control is achieved, but irritation to the eye increases

Engineering Contradiction:
ImprovepH controlVSAvoidirritation
Core Design Contradiction:
Stability of the object's compositionVSObject-affected harmful factors

Solution Approach 1:

The patent introduces buffering agents as intermediary substances that gently regulate pH without causing irritation. These buffering systems act as mediators between the surfactant composition and the sensitive ocular environment, maintaining stable pH levels while avoiding the harsh effects of traditional pH adjusters. This resolves the contradiction by providing pH stability through a gentler mechanism.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively cleans and maintains eyelid hygiene, reducing the risk of bacterial infections by providing a synergistic antimicrobial effect and controlled pH, thus minimizing irritation and promoting regular use for improved ocular health.

Implementation Method 1

The composition consists essentially of purified water, PEG-80 sorbitan laurate, sodium trideceth sulfate, PEG-150 distearate, sodium lauroamphoacetate, cocamidopropyl hydroxysultaine, sodium laureth-13 carboxylate, sodium chloride, PEG-15 cocopolyamine, polyhexamethylene biguanide, potassium sorbate, 1,2 hexanediol, and caprylyl glycol

Methodology Applied
Scientific EffectSurfactant: Surfactant

Implementation Method 2

The use of non-irritating ingredients that also exhibit antimicrobial benefits in the ocular composition increases its cleansing ability

Methodology Applied
Scientific EffectAntimicrobial effect:

Data Source

PatentUS9278079B2Ocular composition and kits thereof
Publication Date: 2016.03.08 OCUSOFT INC

AI summary

An ocular composition consisting essentially of purified water, PEG-80 sorbitan laurate, sodium trideceth sulfate, PEG-150 distearate, sodium lauroamphoacetate, cocamidopropyl hydroxysultaine, sodium laureth-13 carboxylate, sodium chloride, PEG-15 cocopolyamine, polyhexamethylene biguanide, potassium sorbate, 1,2 hexanediol, and caprylyl glycol. The composition can be applied to a fabric pad for use as an eyelid cleanser, where the fabric pad is pre-moistened with the composition and packaged for use. The composition may also be used in an eyelid treatment kit for convenient combination treatments to improve overall eyelid hygiene and adjunctive eyelid therapy.