Ocular Therapeutics Tool Stabilizer for Suprachoroidal Injection
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Solution Overview
Problem
Current methods for delivering drugs to the choroid and retina, such as intravitreal injections, are invasive, poorly targeted, and carry risks like endophthalmitis, hemorrhage, and increased intraocular pressure, whereas suprachoroidal drug delivery offers precise targeting and reduced side effects but requires complex and invasive procedures with microneedles.
Innovation Solution
A stabilizer and injection guide tool that uses regular needles to facilitate safe and accurate suprachoroidal injections by stabilizing the eye, ensuring precise needle placement and depth control, allowing for targeted delivery to the suprachoroidal space without the need for surgical expertise.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If intravitreal injection is used for drug delivery, then the drug can reach the retina and choroid, but the procedure is invasive and carries risks such as endophthalmitis, hemorrhage, and increased intraocular pressure
Solution Approach 1:
The patent introduces a stabilizing device with a hollow body that acts as an intermediary tool between the injector and the eye. This device provides a stable platform and positioning system that enables safer suprachoroidal injection by controlling needle depth and angle, thereby reducing the harmful effects of invasive procedures while maintaining effective drug delivery to the retina and choroid
2Manufacturing precision
If suprachoroidal injection with microneedles is used for precise drug targeting, then the drug delivery precision is improved, but the procedure becomes complex and requires surgical expertise
Solution Approach 1:
The patent divides the injection system into separate functional components: a stabilizing device with hollow body for positioning, a needle guide for depth control, and the injection needle itself. This segmentation allows each component to be optimized independently and simplifies the overall procedure by making the complex task of precise suprachoroidal injection more manageable and accessible to non-surgical personnel
Solution Approach 2:
The hollow body of the stabilizing device serves as an intermediary structure that incorporates built-in depth markers and positioning features. This intermediary tool translates the complex requirements of precise suprachoroidal injection into simple visual cues and mechanical constraints, enabling accurate needle placement without requiring surgical expertise
3Duration of action of moving object
If repeated intravitreal injections are administered to maintain therapeutic drug levels, then the treatment effectiveness is maintained, but the cumulative risk of complications increases
Solution Approach 1:
The stabilizing device with hollow body enables precise suprachoroidal injection as a safer alternative to repeated intravitreal injections. By providing accurate depth control and stable positioning, this intermediary tool allows for effective long-acting drug delivery with lower cumulative risk, thereby maintaining therapeutic effectiveness while improving patient safety over multiple treatment sessions
Data Source
AI summary
An ocular therapeutics tool including a stabilizer including a hollow body and a base connected to the body, the hollow body extending from the base, and the base being adapted to fit the eye surface, and an injection guide connectable to the stabilizer and adapted to receive an injection needle, wherein the injection guide includes at least one stopper adapted to define the injection depth of a needle inserted into the injection guide. The present application also provides an injection guide. The present application also provides a kit with the tool or the injection guide.