Multi-Detector Tear Film Assessment Using Aligned Ocular Surface Data

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Solution Overview

Problem

Existing methods for assessing the tear film are either rudimentary, time-consuming, or require invasive procedures, and dedicated devices often struggle with usability and accuracy.

Innovation Solution

A multi-detector system comprising an OCT device, aberrometer, and reflection topographer, combined with a computer system, analyzes tear film data by identifying signal-to-noise ratios, data inconsistencies, and residual analysis to detect abnormalities in the tear film, generating a graphical representation of the ocular surface with tear film abnormalities.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If dedicated devices are used to assess tear film, then measurement precision is improved, but device complexity and ease of operation deteriorate

Engineering Contradiction:
Improvetear film assessment accuracyVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines multiple measuring devices (OCT device, aberrometer, and reflection topographer) into an integrated system that shares common components such as the optical path, detection system, and control unit. This merging approach maintains high measurement precision through multi-modal data collection while reducing overall device complexity by eliminating redundant components and simplifying operational procedures.

Inventive Principle:
Principle #5Merging (Combining)

2Measurement precision

If dedicated devices are used to assess tear film, then measurement precision is improved, but ease of operation deteriorates

Engineering Contradiction:
Improvetear film assessment accuracyVSAvoidease of operation
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The integrated system is designed to perform multiple tear film assessment functions simultaneously using a single operational workflow. The system can conduct OCT imaging, aberrometry, and topography measurements in one unified process, eliminating the need for separate dedicated devices and simplifying the user experience while maintaining comprehensive measurement precision across all modalities.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Measurement precision

If invasive procedures are used for tear film assessment, then measurement precision is improved, but object-affected harmful factors increase

Engineering Contradiction:
Improvetear film assessment accuracyVSAvoideye surface irritation
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The system utilizes the eye's own reflected light and natural optical properties to generate measurement data. The OCT device, aberrometer, and reflection topographer all rely on light reflected from the eye surface without requiring external dyes, stains, or invasive interventions. This self-service approach enables high-precision tear film assessment while completely avoiding eye surface irritation or damage.

Inventive Principle:
Principle #25Self-service

4Ease of operation

If rudimentary screening methods are used, then ease of operation is improved, but measurement precision deteriorates

Engineering Contradiction:
Improveease of operationVSAvoidtear film assessment accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The system divides the tear film assessment into three distinct measurement segments: OCT imaging for structural analysis, aberrometry for wavefront analysis, and reflection topography for surface mapping. Each segment contributes specific precision advantages, and their integrated analysis through data fusion algorithms provides comprehensive high-precision assessment while maintaining a unified simple user interface that preserves ease of operation.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Provides a comprehensive, non-invasive, and efficient assessment of tear film abnormalities, enhancing the accuracy and usability of tear film analysis.

Implementation Method 1

an optical coherence tomography (OCT) device that directs OCT light towards the eye, detects the OCT light reflected from the eye, and generates OCT data that describes the eye from the reflected OCT light

Methodology Applied
Scientific EffectOptical coherence tomography: Tomography

Implementation Method 2

a wavefront aberrometer subsystem... determines irregular features... by comparing wavefront aberrometry map and corneal topography map

Methodology Applied
Scientific EffectWavefront aberrometry: Interference

Implementation Method 3

a corneal topographer subsystem... generates a corneal topography map... evaluate images of Placido rings reflected from the cornea

Methodology Applied
Scientific EffectPlacido ring reflection: Reflection

Data Source

PatentEP4262517B1Multi-detector analysis of the tear film of an eye
Publication Date: 2026.02.11 ALCON INC
  • EP4262517B1 patent drawingFigure 1
  • EP4262517B1 patent drawingFigure 2A
  • EP4262517B1 patent drawingFigure 2B

AI summary

In certain embodiments, an ophthalmic system for assessing a tear film of an eye comprises measuring devices and a computer. The measuring devices detect light reflected from the eye, where an ocular surface of the eye comprises the tear film, and generate data from the reflected light that describes the eye. The computer aligns the data corresponding to the same location for a plurality of locations, assesses the data at the locations to detect one or more abnormalities of the tear film, and determines a tear film description from the assessment of the data at the locations.