Oculomotor Rehabilitation with Drug-Induced Neuroplasticity Feedback

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Solution Overview

Problem

Existing neurological rehabilitation regimes for oculomotor, visual, and vestibular impairments lack effective methods to leverage pharmacologically induced neuroplasticity for meaningful tracking and feedback during rehabilitation.

Innovation Solution

A method utilizing a neuroplasticity medicament, such as anti-depressants or Brain Derived Neurotrophic Factor enhancers, combined with an oculomotor, visual, and vestibular rehabilitation platform that tracks and records eye movements during tasks, enhancing rehabilitation through controlled neuroplasticity manipulation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional oculomotor, visual, and vestibular rehabilitation tasks are used, then rehabilitation can be performed, but the effectiveness is limited due to lack of neuroplasticity enhancement

Engineering Contradiction:
Improverehabilitation effectivenessVSAvoidrehabilitation efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent changes the physiological parameter of neuroplasticity by administering pharmacological agents (such as SSRIs, BDNF enhancers, or other neuroplasticity-inducing medications) to the subject before or during rehabilitation tasks. This parameter change enhances the brain's ability to reorganize and form new neural connections, thereby improving rehabilitation effectiveness and accelerating recovery progress.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If pharmacological agents are administered to induce neuroplasticity, then rehabilitation effectiveness improves, but the system complexity increases due to need for medication management and monitoring

Engineering Contradiction:
Improveneuroplasticity inductionVSAvoidrehabilitation system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent merges the pharmacological intervention component with the existing oculomotor, visual, and vestibular rehabilitation platform. The medication administration protocol is integrated into the rehabilitation workflow, with timing and dosing coordinated with specific rehabilitation tasks. This combination approach streamlines the overall process while maintaining the benefits of both pharmacological enhancement and targeted rehabilitation exercises.

Inventive Principle:
Principle #5Merging (Combining)

3Measurement precision

If tracking and feedback mechanisms are added to monitor eye movements and rehabilitation progress, then measurement precision improves, but device complexity increases

Engineering Contradiction:
Improveeye movement tracking accuracyVSAvoidrehabilitation platform complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent implements feedback mechanisms that monitor eye movements, head movements, and rehabilitation task performance in real-time. This data is used to provide immediate feedback to the subject about their performance and to automatically adjust rehabilitation task parameters (such as target position, speed, or difficulty level) to optimize training effectiveness. The feedback loop enables precise measurement of progress while guiding the rehabilitation process dynamically.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS12514495B2Neurological rehabilitation and training method utilizing oculomotor, visual and/or vestibular rehabilitation tasks on subjects with pharmacologically induced neuroplasticity
Publication Date: 2026.01.06 NEUROLIGN USA LLC
  • US12514495B2 patent drawing

AI summary

A Neurological Rehabilitation method utilizing oculomotor, visual and/or vestibular rehabilitation tasks on subjects with pharmacologically induced neuroplasticity comprising the steps of Inducing neuroplasticity in a subject through administering of a neuroplasticity medicament; Providing a oculomotor, visual and vestibular rehabilitation task platform configured to supply visual targets to a subject for oculomotor, visual and vestibular rehabilitation tasks and track and record eye movement of the subject during oculomotor, visual and vestibular rehabilitation tasks; Performing oculomotor, visual and/or vestibular rehabilitation tasks on the platform with subjects during periods of pharmacologically induced neuroplasticity. The neuroplasticity medicament generally is comprising at least one of an antidepressant, a Brain Derived Neuro trophic factor enhancer, a steroid, a psychedelic, valproic acid, NDRI's, lithium carbonate, Metformin, N-Acetylcystine, and Human Growth Hormone.