Oleanic Acid Eugenol Oral Care Antibacterial Mixture

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Solution Overview

Problem

Current oral care products face challenges in achieving effective antibacterial efficacy due to interactions with other active ingredients or limitations in the amount of antibacterial agents used, particularly in addressing gum bleeding caused by plaque and gingivitis.

Innovation Solution

An oral care composition incorporating a mixture of oleanic acid and eugenol at a 2:1 to 3:1 weight ratio, which acts as the sole antibacterial agent, enhancing antibacterial effects and providing improved plaque reduction without the need for additional antibacterial agents.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional antibacterial agents are used in oral care products, then plaque and gingivitis are reduced, but antibacterial efficacy is limited due to interactions with other active ingredients or dosage constraints

Engineering Contradiction:

Improveantibacterial efficacyVSAvoidcompatibility with other active ingredients

Core Design Contradiction:

ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines oleanic acid and eugenol into a single antibacterial mixture that works synergistically. This merged approach allows the composition to achieve enhanced antibacterial efficacy without relying on multiple separate antibacterial agents that might interact negatively with other ingredients in the oral care product.

Inventive Principle:

Principle #5Merging (Combining)

Solution Approach 2:

The invention uses a composite antibacterial system consisting of oleanic acid and eugenol in specific ratios (2:1 to 3:1 by weight). This composite material approach creates a more effective antibacterial agent than either component alone, while the defined ratio ensures consistent performance and compatibility within the multi-ingredient oral care formulation.

Inventive Principle:

Principle #40Composite materials

2Reliability

If higher amounts of antibacterial agents are used to improve efficacy, then plaque reduction is enhanced, but the composition may become incompatible with other active ingredients or exceed safe dosage limits

Engineering Contradiction:

Improveplaque reduction efficacyVSAvoidamount of antibacterial agent

Core Design Contradiction:

ReliabilityVSQuantity of substance

Solution Approach 1:

The patent optimizes the concentration parameters of oleanic acid and eugenol within specific ranges (oleanic acid: 0.02-2.0 weight %, eugenol: 0.01-1.0 weight %) to achieve maximum antibacterial efficacy while maintaining compatibility with other ingredients. The specific weight ratio parameter (2:1 to 3:1) is critical for achieving synergistic effects at lower total concentrations.

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The invention applies the principle of local quality by concentrating the antibacterial activity in a specific combination of ingredients (oleanic acid and eugenol) rather than distributing it across multiple agents. This localized approach allows for precise control of the total antibacterial agent quantity while maintaining high efficacy through the synergistic interaction of the two components.

Inventive Principle:

Principle #3Local quality

Data Source

PatentUS11260004B2Oral care composition

Publication Date: 2022.03.01 COLGATE PALMOLIVE CO

AI summary

An oral care composition, including a mixture of antibacterial agents, the mixture of antibacterial agents including oleanic acid and eugenol at a 2:1 to 3:1 weight ratio.