Automated Olfaction Test Device With Alternating Gas Supply

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Solution Overview

Problem

Current olfactory function examinations lack reproducibility and reliability due to manual odor intensity adjustments and adaptation phenomena, making it difficult to perform quantitative and comprehensive assessments, especially in diagnosing conditions like Alzheimer's disease.

Innovation Solution

An olfactory examination apparatus with an odor generating unit that supplies odorous and odorless gases alternately, using mechanisms like odorant cartridges and diffusion tubes to maintain constant concentrations, and a reply unit for verbal responses, ensuring reproducible odor intensity and comprehensive evaluation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual odor intensity adjustment is used, then ease of operation is improved, but reliability and reproducibility deteriorate

Engineering Contradiction:
Improveease of operationVSAvoidreliability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent replaces manual mechanical adjustment of odor intensity with an automated gas concentration control system. A gas supply mechanism delivers odorous gas at precisely controlled concentrations to the examinee, eliminating the need for manual ruler-based distance adjustment. This substitution of mechanical manual operations with an automated gas delivery system ensures both ease of operation and high reliability through consistent, reproducible odor presentation.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Productivity

If continuous odor exposure is used, then comprehensive evaluation is improved, but adaptation phenomenon worsens

Engineering Contradiction:
Improvecomprehensive evaluationVSAvoidreliability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent implements periodic action by alternating between presentation of odorous gas and clean air in a structured sequence. The examinee is exposed to odorous gas for a predetermined period, then to clean air for a reset period, allowing the olfactory system to recover from adaptation. This periodic cycling enables comprehensive evaluation of olfactory function while preventing adaptation-induced measurement errors, thereby maintaining reliability.

Inventive Principle:
Principle #19Periodic action

3Measurement precision

If standardized odor concentration is implemented, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvemeasurement precisionVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent applies parameter changes by utilizing gas concentration as a controllable parameter to achieve standardized odor intensity. Instead of varying physical distance or using complex mechanical adjustment mechanisms, the system precisely controls the concentration parameter of the odorous gas delivered to the examinee. This approach achieves high measurement precision for olfactory function assessment while avoiding excessive device complexity through the use of straightforward gas concentration control.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The apparatus provides a reliable and reproducible method for assessing olfactory function, enabling quantitative evaluation and reducing adaptation effects, thus improving the reliability of olfactory examinations and aiding in early diagnosis of conditions like Alzheimer's disease.

Implementation Method 1

an odorant generating mechanism that stores an odorant and generates an odorous gas having a defined concentration

Methodology Applied
Scientific EffectDiffusion: Diffusion

Data Source

PatentUS10667739B2Olfaction test device
Publication Date: 2020.06.02 SHIMADZU CORP
  • US10667739B2 patent drawing
  • US10667739B2 patent drawing
  • US10667739B2 patent drawing

AI summary

An olfactory examination apparatus includes: an odor generating unit having an odorant generating mechanism that stores an odorant and generates an odorous gas having a defined concentration or an defined intensity and an odorless gas generating mechanism; a gas supply unit configured to alternately supply an odorous gas or an odorless gas having a defined concentration or a defined intensity of the odor from the odorant generating mechanism and the odorless gas generating mechanism to an examinee through an odor presentation mechanism placed on a nostril portion of the examinee, and a reply unit that allows the examinee to express an answer when smelling the odorant in order to examine an olfactory function.