Olive Leaf Extract Oleuropein Concentration via Grape Co-Extraction

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Solution Overview

Problem

Existing methods for producing olive leaf extracts do not optimize for high oleuropein concentration and do not provide clear extraction conditions.

Innovation Solution

A method involving grinding dried olive leaves and mixing them with grapes, using water or alcohol as an extraction solvent at 70°C or higher, with an olive leaf to solvent ratio of 15-35% by weight, to produce an olive leaf extract with high oleuropein content.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If conventional extraction methods are used with water or weak acids, then astringency and bitterness are reduced, but oleuropein concentration remains low

Engineering Contradiction:
Improveastringency and bitternessVSAvoidoleuropein concentration
Core Design Contradiction:
Object-affected harmful factorsVSQuantity of substance

Solution Approach 1:

The patent changes the extraction parameters by using alcohol-containing solvents (10-90% alcohol by volume) instead of pure water or weak acids, and by adjusting extraction temperature (20-100°C) and time (1-48 hours) to simultaneously achieve low astringency/bitterness and high oleuropein concentration

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses composite extraction solvents combining water and alcohol in specific ratios rather than single solvents, creating an optimized extraction medium that balances oleuropein extraction efficiency with sensory quality

Inventive Principle:
Principle #40Composite materials

2Quantity of substance

If extraction temperature is increased to improve oleuropein extraction efficiency, then oleuropein concentration increases, but energy consumption increases

Engineering Contradiction:
Improveoleuropein concentrationVSAvoidextraction energy consumption
Core Design Contradiction:
Quantity of substanceVSUse of energy by moving object

Solution Approach 1:

The patent identifies and applies optimal extraction temperature ranges (20-100°C) that balance extraction efficiency with energy economy, demonstrating that high oleuropein concentration can be achieved without necessarily using maximum temperatures

Inventive Principle:
Principle #35Parameter changes

3Quantity of substance

If extraction time is extended to maximize oleuropein yield, then oleuropein concentration increases, but production time increases

Engineering Contradiction:
Improveoleuropein concentrationVSAvoidextraction time
Core Design Contradiction:
Quantity of substanceVSLoss of time

Solution Approach 1:

The patent determines optimal extraction time ranges (1-48 hours) that achieve maximum oleuropein concentration without excessive time investment, showing that proper solvent composition and temperature can reduce required extraction time

Inventive Principle:
Principle #35Parameter changes

4Quantity of substance

If olive leaf to solvent ratio is increased to improve oleuropein concentration, then extraction efficiency improves, but viscosity of extract increases

Engineering Contradiction:
Improveoleuropein concentrationVSAvoidextract viscosity
Core Design Contradiction:
Quantity of substanceVSStability of the object's composition

Solution Approach 1:

The patent optimizes the olive leaf to solvent ratio and solvent composition to achieve the desired oleuropein concentration while controlling extract viscosity for practical application

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method results in an olive leaf extract with a significantly higher oleuropein concentration, offering enhanced antioxidant and anti-glycation potency, suitable for various applications in medicines, foods, and cosmetics.

Implementation Method 1

extracting an olive leaf extract using an extraction solvent

Methodology Applied
Scientific EffectExtraction: Liquid-Liquid Extraction

Implementation Method 2

extracting an olive leaf extract from the ground olive leaves using an extraction solvent

Methodology Applied
Scientific EffectDiffusion: Diffusion

Implementation Method 3

extraction is performed at 70°C or higher

Methodology Applied
Scientific EffectHeating: Heating

Data Source

PatentEP3323421B1Method for producing an olive leaf extract
Publication Date: 2021.01.13 SHODOSHIMA HEALTHYLAND CO LTD

AI summary

Provided is a method for producing an olive leaf extract that contains a high concentration of oleuropein. The method according to the present invention for producing an olive leaf extract comprises a first step for grinding dried olive leaves and a second step for mixing the ground olive leaves with grape and then extracting an olive leaf extract with the use of an extraction solvent, wherein, in the second step, the extraction solvent is water, an alcohol or a combination thereof and the extraction is conducted at 70°C or higher.