Omega-3 Fatty Acid Amino Acid Salt Tablets
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Solution Overview
Problem
Current omega-3 fatty acid products, particularly in solid forms, face challenges such as low bioavailability, sensitivity to oxidation, high costs, and low concentration, leading to the need for frequent and large doses to achieve recommended daily intake.
Innovation Solution
Development of tablets comprising omega-3 fatty acid amino acid salts with reduced content of binders and structure-forming substances, such as polyvinylpyrrolidone, starch, and calcium phosphate, allowing for high omega-3 fatty acid content and improved bioavailability without the need for additional auxiliaries.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Stability of the object's composition
If omega-3 fatty acid products are formulated with high content of binders and structure-forming substances to ensure tablet stability, then tablet structural integrity is improved, but omega-3 fatty acid content and bioavailability are reduced
Solution Approach 1:
The patent changes the concentration parameter by reducing binder content from conventional levels (typically 30-50% in solid formulations) to minimal or zero levels, while maintaining tablet integrity through the unique properties of omega-3 fatty acid amino acid salts that require no additional binders or structure-forming substances
Solution Approach 2:
The patent extracts and removes binders and structure-forming substances from the formulation, achieving a pure omega-3 fatty acid amino acid salt composition without conventional tablet excipients, thereby maximizing omega-3 content while maintaining structural integrity
2Ease of manufacture
If conventional solid formulations use multiple auxiliaries and binders to ensure manufacturability, then ease of manufacture is improved, but product purity and omega-3 concentration are reduced
Solution Approach 1:
The omega-3 fatty acid amino acid salt serves its own structural and binding functions, eliminating the need for separate binders and structure-forming substances, thereby achieving both high concentration and ease of manufacture through a self-sufficient formulation
Solution Approach 2:
The patent changes the formulation composition parameter by eliminating auxiliary substances entirely, relying solely on the omega-3 fatty acid amino acid salt which inherently possesses all necessary properties for tablet formation without additional manufacturability aids
3Loss of substance
If low concentration formulations are used to reduce costs, then manufacturing cost is reduced, but daily intake requirements necessitate large doses and frequent administration
Solution Approach 1:
The patent changes the concentration parameter by producing ultra-pure omega-3 fatty acid amino acid salts with minimal excipients, enabling high-dose delivery in small tablet quantities, thereby reducing both manufacturing cost per effective dose and the physical burden of administration on consumers
4Reliability
If conventional formulations use animal-derived gelatine or plant-based capsules, then encapsulation and protection are improved, but consumer acceptance is reduced due to religious or dietary restrictions
Solution Approach 1:
The patent extracts and eliminates animal-derived gelatine and plant-based capsule materials from the formulation, replacing them with a pure omega-3 fatty acid amino acid salt tablet that requires no controversial encapsulation materials, thereby achieving universal consumer acceptance while maintaining product integrity
Solution Approach 2:
The patent replaces the conventional capsule encapsulation concept with a direct tablet formulation that inherently provides the same protective and delivery functions without using gelatine or plant-based materials, offering a universally acceptable alternative
Data Source
AI summary
The present invention relates to a tablet comprising one or more omega-3 fatty acid amino acid salt(s), a method for preparing a tablet according to the invention and the use of a tablet according to the invention as a food supplement or as a pharmaceutical product.