On-Diaper Body Fluid Screening Device for Multi-Biomarker Detection
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Solution Overview
Problem
Current 'on-diaper' devices for body fluid analysis are limited in their ability to screen multiple biomarkers and often require painful and inconvenient urine collection procedures, with existing solutions either not being compatible with standard diapers or only capable of detecting a few parameters.
Innovation Solution
A device comprising a stack of sheets including a surface sheet, collection sheet, testing sheet with colorimetric assay reaction pads, protection sheet, and transparent readout sheet, which allows for the simultaneous detection of multiple biomarkers from a single body fluid sample on a standard diaper, with a self-locking mechanism to prevent cross-contamination and maintain sample integrity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If conventional dipsticks are used for body fluid analysis, then multiple biomarkers can be detected, but the sample collection becomes painful and time-consuming
Solution Approach 1:
The patent combines the sample collection function and the detection function into a single integrated device. The diaper-attached device collects body fluid directly through the diaper material and performs multi-biomarker detection within the same unit, eliminating the need for separate collection bottles and dipstick procedures.
Solution Approach 2:
The device serves multiple functions: it acts as both a sample collection system (through its integration with the diaper) and a multi-parameter detection system. The single device can detect multiple biomarkers including but not limited to nitrite, leukocytes, blood, protein, glucose, and pH, replacing both collection containers and test strips.
2Ease of operation
If existing on-diaper devices are used, then sample collection is simplified, but the ability to screen multiple biomarkers is limited
Solution Approach 1:
The device incorporates multiple segmented detection zones, each dedicated to detecting specific biomarkers. The detection area is divided into separate reaction zones for different analytes (nitrite, leukocytes, blood, protein, glucose, pH), allowing simultaneous multi-parameter detection while maintaining the simplified on-diaper collection approach.
3Quantity of substance
If urine is collected in bottles for testing, then adequate sample volume can be obtained, but the procedure becomes painful and time-consuming
Solution Approach 1:
The device utilizes the diaper's existing absorbent structure to automatically collect and concentrate body fluid samples. The diaper material itself serves as the collection mechanism, drawing in and retaining sufficient sample volume through its absorbent properties, eliminating the need for active collection procedures.
4Ease of operation
If the diaper structure is modified to incorporate detection elements, then on-diaper testing is enabled, but compatibility with standard diapers is reduced
Solution Approach 1:
The detection device is designed as a separate, modular unit that attaches to the diaper rather than requiring modification of the diaper structure itself. The device includes distinct functional zones (collection area, detection area, readout area) that can be independently configured and attached to various diaper types.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables the detection of over ten health parameters from a single body fluid sample on a standard diaper, maintaining result accuracy for up to 8 hours without the need for painful sample collection and reducing the risk of contamination, with results readable via a smartphone application.
Implementation Method 1
a testing sheet, which is body fluid absorbent and which is provided with a plurality of colorimetric assay reaction pads
Implementation Method 2
a swelling component arranged in association with the inlet hole and an inlet hole closing member
Implementation Method 3
a surface sheet, which is permeable to body fluid
Implementation Method 4
a collection sheet, which is impervious to body fluid; and a protection sheet, which is impervious to body fluid
Implementation Method 5
a testing sheet, which is body fluid absorbent
Data Source
AI summary
An on-diaper body fluid screening device (100), comprising a stack of the following sheets: a surface sheet (110) permeable to body fluid, a collection sheet (120) impervious to body fluid, a testing sheet (130), which is body fluid absorbent and provided with colorimetric assay reaction pads (131), and which is provided with a body fluid barrier network (132) forming body fluid channels (134) between an inlet section (135) and the colorimetric assay reaction pads (131), a protection sheet (140) impervious to body fluid, and a transparent readout sheet (150), through which the assay reaction pads (131) are visible. The protection sheet (140) comprises pad receiving openings (142). The collection sheet (120) comprises an inlet hole (125) which is arranged over the inlet section (135). A swelling component (702) is arranged in association with the inlet hole (125) and an inlet hole closing member (601).