Dual-Channel Oocyte Retrieval Needle With Transverse Flushing

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Solution Overview

Problem

Current oocyte retrieval methods result in approximately 60% retrieval rates, limiting the chances of success in in-vitro fertilization, and existing apparatuses do not effectively maximize the volume of biological material extracted from intracorporeal sacs.

Innovation Solution

A needle design with a first flow channel for aspiration and a second flow channel for flushing fluid, where the flushing fluid outlet is configured transverse to the aspiration channel, creating vortical structures within the intracorporeal sac to enhance the displacement and movement of biological material.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional aspiration needles are used for oocyte retrieval, then the procedure is simple and quick, but the retrieval rate is limited to approximately 60%

Engineering Contradiction:
Improveoocyte retrieval rateVSAvoidneedle structure complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The needle is divided into functionally distinct segments: a first flow channel for aspiration and a second flow channel for flushing fluid delivery. This segmentation allows simultaneous or sequential performance of multiple functions (aspiration and flushing) that work together to improve retrieval rates beyond what a single-channel needle can achieve

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention merges the aspiration function and flushing function into a single integrated needle device. By combining both flow channels in one needle, the system achieves协同 effect where flushing dislodges oocytes and aspiration simultaneously or sequentially retrieves them, thereby improving overall retrieval efficiency without requiring multiple separate devices

Inventive Principle:
Principle #5Merging (Combining)

2Quantity of substance

If flushing fluid is directed parallel to the aspiration channel, then the device structure is simple, but the volume of biological material extracted is not maximized

Engineering Contradiction:
Improvevolume of biological material extractedVSAvoidoutlet configuration complexity
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The outlet of the second flow channel is configured to direct flushing fluid in a direction substantially transverse (perpendicular) to the first flow channel rather than parallel to it. This dimensional change in fluid delivery creates vortical flow patterns that enhance mixing and displacement of biological material, thereby increasing the volume of material that can be effectively extracted

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Productivity

If multiple aspiration passes are performed to increase retrieval rate, then more oocytes may be retrieved, but the procedure time and patient exposure to invasive procedure increase

Engineering Contradiction:
Improveoocyte retrieval rateVSAvoidprocedure time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The dual-channel needle enables continuous useful action by allowing flushing and aspiration to occur simultaneously or in rapid sequence without requiring device changes or prolonged procedural steps. The flushing action continuously dislodges oocytes while aspiration continuously retrieves them, maintaining effective action throughout the procedure and reducing total time compared to multiple separate aspiration passes

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The new needle design increases the likelihood of successfully retrieving biological material from a larger volume of the intracorporeal sac by promoting vortical flow patterns, improving retrieval rates beyond existing methods.

Implementation Method 1

the outlet is configured to direct the flushing fluid in a direction substantially transverse to the first flow channel... creating vortical structures within the intracorporeal sac to enhance the displacement and movement of biological material

Methodology Applied
Scientific EffectVortical flow: Vortex Ring

Implementation Method 2

a first flow channel comprising an inlet for aspirating biological material from the intracorporeal sac

Methodology Applied
Scientific EffectAspiration: Suction

Data Source

PatentEP4033991B1Needle and uses thereof
Publication Date: 2026.02.11 OXFORD UNIVERSITY INNOVATION LTD
  • EP4033991B1 patent drawingFigure 1a~1b
  • EP4033991B1 patent drawingFigure 2
  • EP4033991B1 patent drawingFigure 3

AI summary

A needle for extraction of biological material from a fluid filled intracorporeal sac, the needle comprising: a shaft comprising a first flow channel comprising an inlet for aspirating biological material from the intracorporeal sac and a second flow channel comprising an outlet for supplying a flushing fluid to the intracorporeal sac; and wherein the outlet is configured to direct the flushing fluid in a direction substantially transverse to the first flow channel; and methods using the needle.