Multimodal Ophthalmic Imaging Head for Accurate OCT-SLO Registration
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Solution Overview
Problem
Existing imaging systems face challenges in accurately registering multi-modality images and achieving high-speed clinical diagnosis for both humans and animals, particularly in ophthalmic applications, due to registration errors and difficulties in adjusting the angle of the subject's eye or organ relative to the imaging system.
Innovation Solution
A multi-modal system that integrates optical coherence tomography (OCT), scanning laser ophthalmoscopy (SLO), adaptive optics enhancement, and OCT-angiography, allowing for simultaneous operation with minimal registration errors and enhanced imaging capabilities, including a modular design with adjustable excitation wavelengths for fluorescence intensity measurement.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If multiple imaging modalities are used simultaneously, then imaging capability and diagnostic information are improved, but registration errors between different modalities increase
Solution Approach 1:
The patent combines multiple imaging modalities (OCT, SLO, adaptive optics, OCT-angiography) into a single integrated system that operates simultaneously from a common platform, allowing synchronized data acquisition and reducing temporal misalignment between modalities
Solution Approach 2:
The patent introduces a common optical path and coordinate system as an intermediary framework that all imaging modalities share, enabling precise spatial registration through a unified reference frame and reducing cumulative alignment errors
2Measurement precision
If the subject's eye or organ is repositioned for imaging, then imaging accuracy is improved, but the time required for diagnosis increases
Solution Approach 1:
Instead of moving the subject's eye or organ to align with the imaging system, the patent inverts the approach by making the imaging head rotatable around the subject, bringing the imaging modalities to the subject rather than vice versa
Solution Approach 2:
The patent implements a dynamically adjustable imaging head that can rotate and reposition around the subject's eye or organ, allowing rapid changes in imaging angle and position without requiring subject repositioning, thereby maintaining imaging accuracy while reducing adjustment time
3Adaptability or versatility
If the imaging system is made more flexible for different subjects, then adaptability is improved, but device complexity increases
Solution Approach 1:
The patent designs a universal imaging head that can perform multiple imaging modalities (OCT, SLO, adaptive optics, OCT-angiography) and can be applied to different subjects including human and animal eyes, reducing the need for multiple specialized devices while maintaining adaptability through software configuration and optical parameter adjustment
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system minimizes registration errors in multi-modality images, enabling high-speed clinical diagnosis and enhanced imaging for both humans and animals, with improved flexibility and accuracy in ophthalmic applications.
Implementation Method 1
optical coherence tomography (OCT) imaging
Implementation Method 2
scanning laser ophthalmoscopy (SLO) (fluorescence and reflectance)
Implementation Method 3
scanning laser ophthalmoscopy (SLO) (fluorescence and reflectance)
Data Source
AI summary
We are presenting a system, and an apparatus for fluorescence imaging, detection and spectroscopy. The device also comprises OCT (Optical Coherence Tomography) imaging. The device can be used for diagnosis, imaging, measurements, evaluation or therapy. The device can be used for ophthalmic imaging and/or diagnosis, or retinal imaging and/or diagnosis. The apparatus and system can be used for the measurement and imaging of the eyes of humans as well as the animals.