Ophthalmic Patient Interface Seals to Limit Tissue Migration

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Solution Overview

Problem

There is a need for further optimization of patient interface options in ophthalmic surgical systems, particularly for creating precise capsulorhexis during cataract surgery, to enhance safety and ease of intraocular lens insertion.

Innovation Solution

A system utilizing an ultrafast laser with a patient interface that projects an optical beam into the eye for three-dimensional scanning, combined with OCT imaging and an aim beam for precise capsulorhexis creation, ensuring accurate focusing and minimizing damage to non-targeted tissue.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional phacoemulsification with ultrasonic tip is used, then nuclear sculpting can be performed, but tissue damage and surgical complexity increase

Engineering Contradiction:
Improvesurgical safetyVSAvoidtissue damage
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces the mechanical ultrasonic phacoemulsification system with a laser-based optical system. The laser creates capsulorhexis and performs nuclear fracturing through photodisruption and photovaporization effects, eliminating the need for mechanical contact between the ultrasonic tip and ocular tissues, thereby reducing tissue damage and surgical complexity

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent utilizes phase transitions of water in ocular tissues through laser-induced photovaporization. The ultrafast laser pulses create localized plasma that rapidly vaporizes water molecules in the target tissue, enabling precise capsulorhexis and nuclear fragmentation without mechanical contact, thus improving surgical safety and reducing harmful mechanical effects

Inventive Principle:
Principle #36Phase transitions

2Manufacturing precision

If laser-assisted capsulorhexis is used, then precision is improved, but device complexity increases

Engineering Contradiction:
Improvecapsulorhexis precisionVSAvoidsystem complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent integrates multiple functions into a single laser system platform. The same ultrafast laser system performs capsulorhexis, nuclear fracturing, cortical removal, and IOL implantation assistance, eliminating the need for multiple separate surgical devices and reducing overall system complexity despite the advanced capabilities of each individual function

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent achieves precise capsulorhexis by controlling laser parameters such as pulse duration (femtosecond to picosecond range), pulse energy, repetition rate, and focal position. By precisely adjusting these parameters, the system creates a smooth circular opening in the anterior capsule with high precision while managing the complexity through programmable control

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If mechanical capsulorhexis instruments are used, then ease of operation is maintained, but manufacturing precision deteriorates

Engineering Contradiction:
Improvesurgical maneuverabilityVSAvoidcapsulorhexis geometry
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The patent replaces manual mechanical instruments with an automated laser system that uses optical focusing and scanning to create capsulorhexis. The laser beam is precisely directed and focused through optical systems and computational control, achieving superior geometric precision compared to manual instruments while maintaining ease of operation through automated sequencing and surgeon guidance

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system enables precise and safe capsulorhexis creation, facilitating easy intraocular lens insertion while reducing complications and improving surgical precision.

Implementation Method 1

an ultrafast laser may then be used to perform a three-dimensional scanned beam ablation pattern that essentially follows the shape of a suture layer of the lens

Methodology Applied
Scientific EffectLaser ablation: Laser Ablation

Implementation Method 2

The pulse energy of the treatment beam is sufficient to produce optical breakdown and initiate a plasma-mediated ablation process

Methodology Applied
Scientific EffectPhotodisruption:

Implementation Method 3

The pulse energy of the treatment beam is sufficient to produce optical breakdown and initiate a plasma-mediated ablation process

Methodology Applied
Scientific EffectOptical breakdown:

Implementation Method 4

The generated treatment beam is then passed through a condensing lens or other focusing device to a focal point within the crystalline lens of the eye

Methodology Applied
Scientific EffectRefraction: Refraction

Implementation Method 5

Optical coherence tomography (OCT) is a noninvasive imaging technology that uses light to take cross-sections of the eye

Methodology Applied
Scientific EffectOptical coherence tomography: Tomography

Data Source

PatentEP4137103B1System for ophthalmic intervention
Publication Date: 2025.12.31 AMO DEVELOPMENT LLC
  • EP4137103B1 patent drawingFigure 1
  • EP4137103B1 patent drawingFigure 2A~2B
  • EP4137103B1 patent drawingFigure 2C

AI summary

One embodiment is directed to a patient interface system for ophthalmic intervention on an eye of a patient, comprising: a housing; an optical lens coupled to the housing and having an optical axis; a eye surface engagement assembly coupled to the housing and comprising an inner seal having an inner seal diameter and being configured to circumferentially engage the eye, an outer seal having an outer seal diameter and being configured to circumferentially engage the eye, and a tissue migration bolster structure configured to be positioned circumferentially between the inner and outer circumferential seals and to prevent migration of tissue of the eye toward the eye surface engagement assembly when a vacuum load is applied within the assembly to cause vacuum engagement of the inner and outer seals against the eye.