Ophthalmological Surgery Control Program Iterative Profile Refinement

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Solution Overview

Problem

Current ophthalmological surgery techniques, such as LASIK, rely on average patient data and simplifications, leading to limited precision in calculating ablation profiles for refractive eye surgery, as they are not specific to individual patients and do not adequately account for physical and biological effects during the surgical process.

Innovation Solution

A computer program and method for generating a control program for ophthalmological surgery that includes a user interface for inputting data, a data receiving interface, a profile change generator, a simulator for simulating treatment results, a judgment stage for evaluating these results, and an iteration loop to adjust control data, ensuring that the ablation profile is individualized and optimized based on pre-given criteria, minimizing errors and deviations from the ideal profile.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If average patient data and simplifications are used to calculate ablation profiles, then the calculation process is simple and fast, but the precision and individualization of the treatment profile deteriorates

Engineering Contradiction:
Improveprecision of ablation profileVSAvoidcomplexity of calculation process
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent applies preliminary action by pre-calculating and storing correction values for various influencing factors (healing process, biomechanical changes, smoothing effects, tear film) in lookup tables before the actual treatment. During treatment, the system simply retrieves and combines these pre-computed values based on measured parameters, avoiding complex real-time calculations while achieving high precision individualized profiles.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent introduces intermediary lookup tables that store pre-computed correction values as intermediate data structures. These tables act as mediators between the measured eye parameters and the final ablation profile, allowing the system to achieve complex individualized results through simple table lookups and combinations rather than complex direct calculations.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Manufacturing precision

If complete simulation and iteration loops are implemented to optimize treatment profiles, then the treatment precision and individualization improve, but the computation time and processing duration increases

Engineering Contradiction:
Improveprecision of treatment profileVSAvoidcomputation time
Core Design Contradiction:
Manufacturing precisionVSLoss of time

Solution Approach 1:

The system performs preliminary calculations and stores correction values for all major influencing factors in lookup tables before treatment. This pre-computation eliminates the need for time-consuming iterative simulations during the actual treatment planning, as the system only needs to retrieve and combine pre-computed values based on the patient's specific measurements.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent implements a hybrid approach where only essential iterations are performed - specifically iterating to converge the ablation profile to match the desired postoperative shape within tolerance, while using pre-computed lookup tables for all correction factors. This partial iteration approach achieves sufficient precision without the excessive computation time of complete iterative simulations.

Inventive Principle:
Principle #16Partial or excessive action

3Measurement precision

If multiple influencing factors (healing process, biomechanical changes, smoothing effects, tear film) are considered in the ablation profile calculation, then the accuracy of predicting actual treatment results improves, but the complexity of the calculation process increases

Engineering Contradiction:
Improveaccuracy of treatment result predictionVSAvoidcomplexity of calculation process
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent segments the complex calculation of multiple influencing factors into separate, independent correction values for each factor (healing process correction, biomechanical changes correction, smoothing effects correction, tear film correction). Each factor is calculated and stored separately in lookup tables, then combined during treatment planning. This segmentation allows accurate consideration of all factors while keeping the calculation process manageable through modular organization.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses lookup tables as intermediary data structures to store pre-computed correction values for each influencing factor. These tables serve as mediators that translate complex physical and biological effects into simple, retrievable correction values that can be easily combined with the basic ablation profile without requiring complex real-time calculations.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for precise and personalized refractive eye surgery by iteratively refining the ablation profile, ensuring that the final result meets pre-defined tolerances, thereby improving surgical outcomes and minimizing errors in the treatment process.

Implementation Method 1

the re-shaping of the cornea by ablation (removal of tissue)

Methodology Applied
Scientific EffectLaser ablation: Laser Ablation

Implementation Method 2

ablation profile representing a well-defined volume of tissue to be ablated from a cornea

Methodology Applied
Scientific EffectAblation: Ablation

Implementation Method 3

The positioning is performed in three dimensions wherein the x, y-plane is perpendicular to the line of sight, whereas the z-axis is in that line. The z-coordinate, therefore, is related to the focusing of the laser beam.

Methodology Applied
Scientific EffectPhotodisruption: Photodissociation

Data Source

PatentUS10729585B2Computer program for ophthalmological surgery
Publication Date: 2020.08.04 ALCON INC
  • US10729585B2 patent drawing
  • US10729585B2 patent drawing
  • US10729585B2 patent drawing

AI summary

A Computer program for determining a working profile for controlling a radiation system in refractive eye surgery, said program comprising:a user interface for input of data by a user; a data receiving interface for receiving measured data regarding the eye to be corrected; a working profile generator for generating a working profile on the basis of the input data and measured data; a generator for generating control data for controlling electromagnetic radiation; a simulator for simulating a treatment result on the basis of said control data for controlling the electromagnetic radiation and the effect of said radiation on eye tissue; a judgment stage for judging said treatment results by applying pre-given criteria; an iteration loop for generating iteratively, in case of a negative judgment, another amended profile on the basis of other data or for generating iteratively other control data for controlling the electromagnetic radiation; and a transfer means for transferring control data to a control of the radiation system in case of a positive judgment in the judgment stage.