OPN5 Light Radiation System for 380 nm Myopia Progression Control
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Solution Overview
Problem
Existing technologies have not effectively utilized the activation of Opsin 5 (OPN5) photoreceptor protein in the human retina for improving visual and non-visual functions, particularly in preventing and suppressing myopia progression.
Innovation Solution
A light radiation system and method that includes one or more light sources emitting wavelengths overlapping the peak absorption spectrum of OPN5, with adjustable conditions such as installation position, radiation direction, wavelength range, irradiance, time frame, and duration, to activate OPN5 in the retina.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If light sources are configured to radiate light overlapping the peak wavelength of OPN5 absorption spectrum (380 nm), then OPN5 activation and visual function improvement are enhanced, but device complexity and configuration requirements increase
Solution Approach 1:
The patent applies parameter changes by specifying precise wavelength parameters (360-400 nm range with peak at 380 nm) to match OPN5 absorption characteristics. This resolves the contradiction by transforming the complex biological requirement into a concrete, measurable physical parameter that can be directly controlled by light source selection and spectral configuration, thereby ensuring reliable OPN5 activation without excessive system complexity
Solution Approach 2:
The patent implements preliminary action by pre-defining the optimal wavelength range (360-400 nm) and peak wavelength (380 nm) based on OPN5 absorption spectrum characteristics before actual light radiation. This allows the system to be configured in advance with appropriate light sources and spectral filters, eliminating the need for complex real-time adjustments during operation and simplifying the overall device configuration
2Productivity
If multiple light sources with specific conditions are used to optimize OPN5 activation, then light radiation effectiveness is improved, but system complexity and control requirements increase
Solution Approach 1:
The patent applies segmentation by dividing the light radiation system into multiple independent light sources, each configured with specific wavelength ranges and irradiance levels. This allows the complex task of achieving optimal OPN5 activation to be broken down into simpler, independently controllable units, where each light source contributes a specific portion of the required spectral output, thereby improving overall effectiveness while managing system complexity through modular design
Solution Approach 2:
The patent implements universality by designing a multi-functional light radiation system where multiple light sources serve both individual and collective functions. Each light source can operate independently with specific wavelength characteristics, while collectively they achieve the comprehensive spectral coverage needed for optimal OPN5 activation, allowing the system to adapt to different operational requirements without increasing control complexity
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system effectively activates OPN5, potentially improving visual functions and preventing myopia progression by optimizing light exposure based on spectral data comparisons and irradiance levels.
Implementation Method 1
one or two or more light sources that radiate light having a wavelength in a wavelength region overlapping a peak wavelength of an OPN5 absorption spectrum
Implementation Method 2
OPN5 exhibits an absorption spectrum having a peak at 380 nm
Data Source
AI summary
A light radiation system includes one or more light sources that radiate light having a wavelength in a wavelength region overlapping a peak wavelength of an OPN5 absorption spectrum. One or two or more conditions selected from an installation position, a radiation direction of the light, a wavelength range of the light, an irradiance of the light, a radiation time frame of the light, and a radiation duration of the light of each of the one or two or more light sources are regulated. A light radiation system includes a light radiating means including the one or more light sources and a light measuring means for measuring spectral data of the light and comparing the spectral data of the light and data of the OPN5 absorption spectrum, and configured to regulate an installation position and the like of each light source on the basis of results obtained by the comparison.