Optical Analysis System Temperature Compensation
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Solution Overview
Problem
Existing optical analysis systems face challenges in accurately measuring light intensity due to interfering factors, requiring complex and costly instrumentation for precise spectral analysis, and lack the ability to analyze reflected or transmitted light in real-time or near real-time.
Innovation Solution
The use of multivariate optical elements and high-speed processing methods to illuminate samples and detect light signals, allowing for real-time analysis of spectral-specific light through a system that includes a light source, spectral elements, and detectors, with temperature compensation to enhance measurement precision and stability.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional optical analysis systems are used to measure light intensity, then measurement capability is provided, but measurement precision deteriorates due to interfering factors and inability to separate contributing variables
Solution Approach 1:
The patent segments the light spectrum into multiple wavelength bands using bandpass filters, allowing independent measurement of each band's intensity. This segmentation enables the system to separate the contribution of different spectral features to the total light intensity, thereby improving measurement precision without requiring overly complex instrumentation.
Solution Approach 2:
The patent transitions from measuring a single light intensity value to measuring multiple intensity values across different wavelength bands. By adding the dimension of wavelength separation, the system can distinguish between different contributing factors to light intensity, resolving the measurement precision problem through multi-dimensional data collection.
2Measurement precision
If multiple linear regression is performed to estimate sample properties from light intensity data, then information derivation is achieved, but measurement precision deteriorates due to unknown interfering factors
Solution Approach 1:
The patent extracts specific wavelength bands from the overall light spectrum using bandpass filters, isolating the spectral regions most relevant to the sample properties being measured. By taking out only the necessary spectral information and discarding irrelevant data, the system reduces the impact of unknown interfering factors while maintaining estimation precision.
Solution Approach 2:
The patent changes the measurement parameters from a single total light intensity to multiple wavelength-specific intensities. This parameter transformation allows the system to account for different spectral contributions separately, improving the precision of sample property estimates by reducing the confounding effect of unknown interfering factors.
3Measurement precision
If spectral analysis is performed to separate wavelength bands, then measurement precision improves, but device complexity and cost increase due to requirement for spectrographs and multiple detectors
Solution Approach 1:
Instead of using a complex spectrograph to dispersively separate wavelengths, the patent segments the spectrum using multiple bandpass filters, each tuned to a specific wavelength band. This approach achieves spectral separation with simpler, more cost-effective optical components while maintaining measurement precision.
Solution Approach 2:
The patent uses multiple detectors to simultaneously measure the intensity of different wavelength bands, creating parallel measurement paths rather than using a single complex dispersive system. This copying approach simplifies the instrumentation while preserving the ability to perform precise spectral analysis.
4Productivity
If real-time analysis is implemented using conventional systems, then productivity improves, but measurement precision deteriorates due to lack of temperature compensation and environmental stability
Solution Approach 1:
The patent incorporates temperature sensors that continuously monitor the optical path and provide feedback signals to compensate for temperature-induced drift in the measurement system. This feedback mechanism maintains measurement precision during real-time analysis by dynamically adjusting for environmental changes.
Solution Approach 2:
The system performs preliminary temperature measurements and applies compensation factors before final analysis is completed. By anticipating and compensating for temperature effects in advance, the system maintains measurement stability even during rapid real-time processing.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables high-speed, accurate monitoring of sample properties by processing light signals in real-time, reducing the need for complex instrumentation and improving measurement precision, allowing for continuous, in-line analysis of various materials during processing.
Implementation Method 1
illuminating at least one portion of the pharmaceutical product with a spectral-specific light
Implementation Method 2
reflecting light carrying information about the portion through at least one multivariate optical element to produce a first signal
Implementation Method 3
detecting the first signal at a first detector
Data Source
AI summary
The present subject matter relates to methods of high-speed analysis of product samples. Light is directed to a portion of a product under analysis and reflected from or transmitted through the product toward an optical detector. Signals for the detector are compared with reference signals based on a portion of the illuminating light passing through a reference element to determine characteristics of the product under analysis. Temperature within the analysis system is monitored and the output signals of the optical detectors are compensated or corrections are made within the analysis calculations to compensate or correct for the system temperature. The products under analysis may be stationary, moved by an inspection point by conveyor or other means, or may be contained within a container, the container including a window portion through which the product illuminating light may pass.