Optical Analyte Testing Using Fluorescence Spectral Imaging

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Solution Overview

Problem

Existing blood glucose testing methods are invasive, require disposable needles, are prone to errors due to test strip degradation, and involve complex operations, while non-invasive methods are cumbersome and require phase adjustments.

Innovation Solution

A system utilizing a light source, imaging spectrum detection apparatus, and controller to provide light within a preset wavelength range, capturing images and spectral data without electrochemical reactions, enabling non-invasive testing through fluorescence spectroscopy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If electrochemical measurement methods (glucose oxidase electrode or glucose dehydrogenase electrode) are used, then blood glucose values can be obtained through test strips, but the test strips are not easy to preserve, easily deteriorate due to preservation environment influence, and require invasive blood sampling

Engineering Contradiction:
Improveblood glucose measurementVSAvoidtest strip stability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent replaces the electrochemical measurement system with an optical measurement system. Instead of using electrochemical reactions between test strips and blood glucose, the invention uses light sources to illuminate the measurement area and optical sensors to detect light absorption or scattering changes that correlate with glucose concentration. This substitution eliminates the need for test strips and their associated preservation issues, while maintaining measurement capability through a different physical principle.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If invasive blood sampling is performed using blood sampling needles, then blood glucose can be measured, but the needles can only be used once and need to be discarded, resulting in resource waste

Engineering Contradiction:
Improveblood glucose measurementVSAvoidblood sampling needle
Core Design Contradiction:
Measurement precisionVSLoss of substance

Solution Approach 1:

The patent replaces the mechanical invasive sampling system with a non-invasive optical measurement system. Instead of using needles to extract blood samples, the invention uses light to probe the measurement area (likely through tissue or fluid) and detect glucose concentration optically. This eliminates the need for disposable needles and blood collection, thereby preventing resource waste while achieving the same measurement objective.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Measurement precision

If phase modulator groups with 180° phase difference are used in blood glucose spectrum testing, then testing can be performed, but phase difference adjustment is required and the optical path structure becomes complicated

Engineering Contradiction:
Improveblood glucose spectrum testingVSAvoidoptical path structure
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts and removes the complex phase modulator groups from the optical measurement system. Instead of using multiple light sources with phase modulators requiring 180° phase difference adjustment, the invention employs a simplified optical path that achieves blood glucose spectrum testing without these complex components. This extraction of unnecessary elements directly reduces device complexity while preserving the core measurement function.

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Facilitates easy, non-invasive testing with reduced resource waste, accurate analyte concentration measurement, and real-time results by excluding non-analyte influences, achieving high accuracy and comfort.

Implementation Method 1

a light source, capable of providing light within a preset wavelength range

Methodology Applied
Scientific EffectLight: Light

Implementation Method 2

enabling non-invasive testing through fluorescence spectroscopy

Methodology Applied
Scientific EffectFluorescence spectroscopy: Fluorescence

Data Source

PatentUS20260023013A1System and apparatus for testing analyte
Publication Date: 2026.01.22 SENSURA PTE LTD
  • US20260023013A1 patent drawing
  • US20260023013A1 patent drawing
  • US20260023013A1 patent drawing

AI summary

The present invention provides a system and an apparatus for testing an analyte which relate to the field of optical analysis. The system for testing the analyte includes a light source, an imaging spectrum detection apparatus, and a controller. The controller establishes an electric connection or communication connection with the light source and the imaging spectrum detection apparatus separately, and the light source is capable of providing light within a preset wavelength range; and under the effect of the controller, the light source provides the light within the preset wavelength range to a specified area, and the imaging spectrum detection apparatus images the specified area to obtain a corresponding image and/or spectral data.