Optical Biomodule for Early Disease Detection

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Solution Overview

Problem

Current technologies lack effective solutions for simultaneously managing the risks of Alzheimer's, Cardiovascular, and Diabetes diseases, particularly in addressing the interconnected risk factors and complications associated with these conditions, such as insulin resistance and amyloid beta production.

Innovation Solution

Development of chemical compositions and delivery systems, including bioactive compounds and nanodelivery methods, integrated with diagnostic biomodules for targeted delivery and detection of disease-specific biomarkers, along with a wearable augmented reality subsystem connected with ambient sensors for personalized healthcare.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If current technologies are used for disease detection and management, then existing diagnostic capabilities are maintained, but they fail to effectively address interconnected risk factors of Alzheimer's, Cardiovascular, and Diabetes diseases simultaneously

Engineering Contradiction:

Improveability to manage multiple disease risksVSAvoideffectiveness in addressing interconnected risk factors

Core Design Contradiction:

Adaptability or versatilityVSReliability

Solution Approach 1:

The patent integrates multiple diagnostic functions into a single optical biomodule that can detect biomarkers for Alzheimer's, Cardiovascular, and Diabetes diseases simultaneously. The system uses a unified platform with light sources, waveguides, and sensors that can identify multiple disease-specific biomarkers (such as amyloid beta for Alzheimer's, glucose metabolites for Diabetes, and cardiovascular markers) in a single test, enabling one device to perform multiple diagnostic functions that were previously required separate systems

Inventive Principle:

Principle #6Universality (Multi-functionality)

Solution Approach 2:

The invention combines chemical compositions for lowering disease risks with diagnostic detection capabilities and nanodelivery systems into an integrated platform. The system merges prevention (chemical compositions), detection (optical biomodule), and treatment (nanodelivery) functions into a cohesive system that addresses the full spectrum of disease management for Alzheimer's, Cardiovascular, and Diabetes conditions

Inventive Principle:

Principle #5Merging (Combining)

2Productivity

If traditional diagnostic systems are used, then basic detection functions are provided, but real-time monitoring and personalized healthcare outcomes are not achieved

Engineering Contradiction:

Improvereal-time monitoring capabilityVSAvoidintegrated diagnostic and delivery system

Core Design Contradiction:

ProductivityVSDevice complexity

Solution Approach 1:

The patent employs a nested structure where the optical biomodule is integrated within a larger wearable augmented reality subsystem. The biomodule itself contains nested components including light sources, waveguides, and sensors arranged in a compact configuration. This nested architecture allows the complex integrated system to be miniaturized and worn on the body, enabling real-time monitoring while managing device complexity through hierarchical integration

Inventive Principle:

Principle #7Nested doll (Nesting)

Solution Approach 2:

The system incorporates ambient sensors that automatically detect and monitor disease-related parameters without requiring manual intervention. The wearable augmented reality subsystem continuously collects data from the optical biomodule and ambient sensors, processes information in real-time, and provides personalized healthcare feedback automatically, enabling the system to serve itself and the user without constant medical professional involvement

Inventive Principle:

Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The proposed solution effectively lowers the risks of Alzheimer's, Cardiovascular, and Diabetes diseases by using bioactive compounds for targeted treatment and diagnosis, while the integrated diagnostic and delivery system provides real-time monitoring and intervention, enhancing personalized healthcare outcomes.

Implementation Method 1

Optical biomodule for detection of diseases at an early onset

Methodology Applied

Scientific EffectOptical detection:

Data Source

PatentUS20250093345A1Optical biomodule for detection of diseases at an early onset

Publication Date: 2025.03.20 MAZED MOHAMMAD A

AI summary

An optical biomodule for detecting a disease specific biomarker(s) at an early stage, utilizing enhanced fluorescence emission (due to integration of three-dimensional (3-D) structures in a fluidic container) upon chemical binding/coupling of a disease specific biomarker(s) with its corresponding disease specific biomarker binder(s)-coupled with a fluorophore(s) positioned horizontally within a geometrical area (that includes a center region or a middle region) is disclosed. Furthermore, a corresponding disease specific biomarker binder(s) may include an amplifying chemical structure/sequence. The three-dimensional (3-D) structure(s) may be coupled with an optical resonator and/or a photonic crystal (PC) and/or a metamaterial and/or a metamaterial of Epsilon-Near-Zero (ENZ) of a suitable wavelength range.