Optical System Calibration via Dynamic Light Source Brightness Control

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Solution Overview

Problem

Current biophotonic systems face limitations in real-time, point-of-care diagnostics due to issues with calibration accuracy and efficiency, leading to unnecessary recalibrations and delays, especially when dealing with body fluids or environmental samples.

Innovation Solution

A method and optical system that controls the brightness of the light source during calibration to prevent overdriving the spectrometer, allowing for precise calibration and reducing unnecessary recalibrations by comparing measured spectra to detect changes in measurement behavior, thereby optimizing signal-to-noise ratio and minimizing noise influence.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If the light source operates at nominal brightness during calibration, then the calibration process is faster, but the spectrometer may be overdriven leading to inaccurate measurements

Engineering Contradiction:
Improvecalibration speedVSAvoidcalibration accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The light source brightness is dynamically adjusted based on the calibration needs. During calibration, the brightness is reduced to prevent spectrometer overdrive, while during actual measurements, the brightness returns to nominal levels. This dynamic adaptation resolves the contradiction between calibration speed and accuracy.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent changes the operating parameter (brightness) of the light source depending on the operational mode. By switching between reduced brightness (calibration mode) and nominal brightness (measurement mode), the system optimizes both calibration precision and measurement efficiency, resolving the technical contradiction.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If regular recalibration is performed based on time or duty cycle, then measurement precision is maintained, but unnecessary delays and downtimes occur

Engineering Contradiction:
Improvemeasurement precisionVSAvoidrecalibration downtime
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system implements feedback-based calibration triggering by continuously monitoring measurement spectra for changes in behavior. When spectral patterns indicate drift or when correlation thresholds are exceeded, recalibration is automatically triggered. This feedback mechanism eliminates unnecessary regular recalibrations while maintaining measurement precision.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The optical system performs self-diagnosis by comparing current spectra with historical data and automatically determines when recalibration is needed. This self-service approach replaces manual time-based scheduling with intelligent, need-based calibration triggering, reducing downtime while maintaining precision.

Inventive Principle:
Principle #25Self-service

3Adaptability or versatility

If different hardware references are used for calibration and measurement, then calibration flexibility is improved, but system complexity and potential errors increase

Engineering Contradiction:
Improvecalibration flexibilityVSAvoidsystem complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent makes the light source serve dual functions: it is used both for illumination during measurements and as the calibration reference source. This universal use of a single component eliminates the need for separate calibration hardware, reducing system complexity while maintaining calibration flexibility through software-based reference management.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution enables exact and reliable calibration, reduces unnecessary recalibrations and delays, and improves the signal-to-noise ratio, resulting in more accurate and efficient diagnostic measurements for biophotonic systems.

Implementation Method 1

a light source (5) for illuminating the chamber (26) with light

Methodology Applied
Scientific EffectLight emission: Light Emitting Diode

Implementation Method 2

a spectrometer (6) for measuring a spectrum of light originating from the chamber (26)

Methodology Applied
Scientific EffectSpectral measurement: Absorption Spectroscopy

Implementation Method 3

overdriving the spectrometer receiving light from the light source, in particular by means of reflection and/or scattering by the chamber or by the element received therein

Methodology Applied
Scientific EffectLight reflection: Reflection

Implementation Method 4

overdriving the spectrometer receiving light from the light source, in particular by means of reflection and/or scattering by the chamber or by the element received therein

Methodology Applied
Scientific EffectLight scattering: Scattering

Data Source

PatentUS20240328930A1Method for calibrating an optical system
Publication Date: 2024.10.03 BOEHRINGER INGELHEIM VETMEDICA GMBH
  • US20240328930A1 patent drawing
  • US20240328930A1 patent drawing
  • US20240328930A1 patent drawing

AI summary

A method for calibrating an optical system that has a chamber for receiving an element of body fluid or tissue or environmental sample uses a light source for illuminating the chamber with light, and a spectrometer for measuring a spectrum of light originating from the chamber, wherein the brightness of the light source is controlled while measuring a spectrum for calibration with the spectrometer so that the brightness of the light source is a reduced brightness, a brightness reduced relative to a nominal brightness of the light source, and/or a brightness reduced relative to a brightness of the light source when measuring the spectrum of the element; and/or wherein a spectrometer of the optical system is monitored with regard to a changed measurement behavior and upon detection of the changed measurement behavior of the spectrometer a calibration. Preferably spectra of preceding measurements are compared with each other.