Optical Cavity Analyte Detection via Photosensing Array

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Solution Overview

Problem

Current techniques face challenges in obtaining high-resolution, rapid analysis of optical characteristics of analytes using optical cavity output light, often requiring bulky equipment and struggling with noise and the need for multiple techniques to capture various optical characteristics simultaneously.

Innovation Solution

The system involves photosensing optical cavity output light while analytes move relative to an array of photosensing elements, using relative motion between analytes and optical cavities to encode information in the output light, allowing for simultaneous high spectral and spatial resolution analysis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional optical analysis techniques are used to obtain high-resolution spectral information, then measurement precision is improved, but device complexity and size increase

Engineering Contradiction:
Improvespectral resolutionVSAvoidequipment size
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system divides the optical detection function into discrete photodetector elements arranged in an array, where each element captures light at a specific spatial position. This segmentation allows spectral information to be distributed across multiple simple detectors rather than requiring a single complex spectrometer, thereby reducing overall device complexity while maintaining high spectral resolution through the spatial distribution of detection elements.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention replaces traditional mechanical scanning spectrometers with a static photodetector array system. Instead of using moving mirrors or rotating gratings to disperse light, the system uses a fixed optical cavity coupled with an array of photodetectors that simultaneously capture spectral information. This substitution eliminates mechanical complexity and reduces device size while maintaining measurement precision.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Adaptability or versatility

If multiple optical characteristics are measured simultaneously using multiple techniques, then measurement completeness is improved, but device complexity increases

Engineering Contradiction:
Improvemeasurement completenessVSAvoidsystem complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The optical cavity-photodetector array system serves multiple measurement functions simultaneously. The same basic configuration can measure absorption spectra, fluorescence emission, and other optical characteristics by simply changing the excitation source or detection wavelength range, without requiring separate dedicated instruments for each measurement type. This multi-functionality improves measurement completeness while avoiding the complexity of multiple separate systems.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The invention merges the optical cavity resonance enhancement function with the photodetector array detection function into a single integrated system. By combining these functions, the system achieves simultaneous high spectral resolution and the ability to measure multiple optical characteristics without requiring separate instruments, thereby improving versatility while controlling system complexity.

Inventive Principle:
Principle #5Merging (Combining)

3Productivity

If rapid analysis is achieved by reducing measurement time, then productivity is improved, but measurement precision may deteriorate

Engineering Contradiction:
Improveanalysis speedVSAvoidsignal accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system utilizes the periodic resonance characteristics of the optical cavity, where light circulates multiple times through the cavity at resonant frequencies. This periodic circulation of light effectively multiplies the interaction time between light and analyte without increasing the overall measurement time, thereby maintaining high signal accuracy while enabling rapid analysis. The resonance enhancement allows sufficient signal accumulation in a short time period.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The optical cavity performs preliminary signal enhancement by circulating and amplifying the light signal before it reaches the photodetectors. This preliminary action of resonance enhancement ensures that sufficient signal strength is achieved before detection, allowing rapid measurements without sacrificing precision. The cavity pre-conditiones the light to maximize information content in each measurement cycle.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables efficient, high-resolution, and rapid analysis of optical characteristics, reducing the need for bulky equipment and allowing for accurate simultaneous measurement of multiple optical characteristics, improving the accuracy and efficiency of analyte analysis.

Implementation Method 1

A homogeneous optical cavity provides output light with a laterally varying intensity function that depends on both photon energy and lateral position

Methodology Applied
Scientific EffectOptical cavity resonance: Resonance

Implementation Method 2

The cell's effective RI can be computed by monitoring wavelength and power

Methodology Applied
Scientific EffectRefraction: Refraction

Implementation Method 3

photosensing an optical cavity's output light with an array of photosensing elements

Methodology Applied
Scientific EffectPhotoelectric effect: Photoelectric Effect

Data Source

PatentUS7554673B2Obtaining information about analytes using optical cavity output light
Publication Date: 2009.06.30 GENESEE VALLEY INNOVATIONS LLC
  • US7554673B2 patent drawing
  • US7554673B2 patent drawing
  • US7554673B2 patent drawing

AI summary

While two or more analytes within an optical cavity move relative to an array of photosensing elements, the cavity provides output light that has a position/time varying intensity function that depends on optical characteristics of the analytes and on the relative movement. The output light is photosensed to obtain sensing results that depend on the position/time varying intensity function. The sensing results are used to obtain information about at least one of the analytes. The relative movement can, for example, be caused by moving analytes within channels within the cavity, such as by causing flow of a medium that carries the analytes through the channels. Or the analytes can be in wells of a biochip, with the cavity defined by reflective slides on opposite surfaces of the biochip, and the slides and biochip can be caused to move together relative to the array.