Optical Fiber Clot Composition Analysis

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current medical technologies cannot accurately identify the composition of brain clots, which is crucial for selecting the appropriate clot removal device, as existing imaging methods like CT and fluoroscopy cannot differentiate between clots composed of red blood cells and white blood cells, affecting the success of clot removal procedures.

Innovation Solution

A medical system incorporating optical fibers and an electrooptical measurement unit that guides and measures optical signals interacting with brain clots, using monochromatic red light and Bragg grating sensors to analyze the composition of clots, and a processor to recommend the appropriate clot removal device based on the analysis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If CT or fluoroscopy imaging methods are used to detect brain clots, then the detection capability is sufficient for locating clots, but the measurement precision of clot composition is insufficient as these methods cannot differentiate between red blood cell and white blood cell clots

Engineering Contradiction:
Improveclot composition identificationVSAvoidimaging system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces mechanical imaging systems (CT, fluoroscopy) with an optical-based detection system. Optical fibers deliver light to the clot and collect scattered light, which is then analyzed to determine clot composition. This substitution enables differentiation between red and white blood cell clots based on their distinct optical scattering properties, achieving composition-level measurement precision that mechanical imaging cannot provide.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If optical fibers are used to guide light for clot analysis, then the measurement precision of clot composition improves, but the device complexity increases due to integration of optical components

Engineering Contradiction:
Improveclot composition analysisVSAvoidoptical system integration
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The catheter is designed as a multi-functional device that combines mechanical navigation capabilities with optical detection functions. The same catheter structure that delivers the device to the clot site also houses the optical fibers for light delivery and collection. This integration allows a single device to perform both mechanical delivery and optical analysis, reducing the need for separate specialized equipment while achieving precise clot composition measurement.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Adaptability or versatility

If a processor is added to analyze optical signals and recommend stent selection, then the adaptability of the treatment system improves, but the device complexity increases

Engineering Contradiction:
Improvestent selection adaptabilityVSAvoidprocessing system complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system implements a feedback loop where optical signals from the clot are analyzed by a processor to determine clot composition, which then feeds back into the treatment decision-making process. The processor provides real-time information about whether the clot is composed of red or white blood cells, enabling the physician to select the appropriate stent type (red cell stent or white cell stent) based on the analyzed data. This feedback mechanism enhances treatment adaptability by matching the stent type to the specific clot composition.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables accurate identification of clot composition, improving the success rate of clot removal by recommending the optimal stent type for engaging and removing the clot, thereby enhancing clinical outcomes in emergency catheterization procedures.

Implementation Method 1

one or more optical fibers configured to guide an optical signal to be transmitted via the brain clot, or to be reflected from the brain clot

Methodology Applied
Scientific EffectOptical fiber light transmission: Optical Fibre

Implementation Method 2

The optical signal includes monochromatic red light... and Bragg grating sensors to analyze the composition of clots

Methodology Applied
Scientific EffectBragg reflection: Bragg Diffraction

Data Source

PatentUS11064920B2Brain clot characterization using optical signal analysis, and corresponding stent selection
Publication Date: 2021.07.20 BIOSENSE WEBSTER (ISRAEL) LTD
  • US11064920B2 patent drawing
  • US11064920B2 patent drawing
  • US11064920B2 patent drawing

AI summary

A medical system includes a probe, an electrooptical measurement unit, and a processor. The probe, which is configured for insertion into a blood vessel of a brain, includes one or more optical fibers configured to guide an optical signal to interact with a brain clot in the blood vessel, and to output the optical signal that interacted with the brain clot. The electrooptical measurement unit is configured to collect and measure the outputted optical signal. The processor is configured to identify a composition of the brain clot by analyzing the measured optical signal from the probe.