Non-Invasive Compartment Syndrome Detector Using Optical Oxygen Saturation

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Solution Overview

Problem

Current methods for diagnosing acute compartment syndrome (ACS) are invasive, requiring trained specialists and are not suitable for pre-hospital or emergency room settings.

Innovation Solution

A non-invasive hand-held apparatus equipped with an optical sensor for detecting oxygen saturation, a pressure sensor, and an ultrasound probe to determine compartment pressure and stiffness, allowing for early detection of ACS without penetrating the skin.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If needle or catheter insertion method is used to measure ICP, then measurement precision is improved, but device complexity and ease of operation worsen due to invasive procedure requiring trained specialists

Engineering Contradiction:
ImproveICP measurement accuracyVSAvoidease of operation
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The patent replaces the mechanical needle insertion system with an optical detection system. The optical sensor uses light absorption properties of hemoglobin to measure tissue oxygen saturation and infer compartment pressure, eliminating the need for physical penetration and specialized training while maintaining diagnostic accuracy.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces optical sensors as an intermediary between the measurement goal and the tissue. Instead of directly inserting a needle into the muscle compartment, the system uses light as a mediator to indirectly measure tissue conditions through optical absorption spectroscopy, making the procedure non-invasive and easier to perform.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If needle or catheter insertion method is used to measure ICP, then measurement precision is improved, but device complexity worsens due to invasive procedure requiring trained specialists

Engineering Contradiction:
ImproveICP measurement accuracyVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces the mechanical needle insertion system with an optical detection system. The optical sensor uses light absorption properties of hemoglobin to measure tissue oxygen saturation and infer compartment pressure, eliminating the need for physical penetration and specialized training while maintaining diagnostic accuracy.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Measurement precision

If needle or catheter insertion method is used to measure ICP, then measurement precision is improved, but loss of time worsens due to requirement of trained specialists and invasive procedure

Engineering Contradiction:
ImproveICP measurement accuracyVSAvoidtime for diagnosis
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent replaces the mechanical needle insertion system with an optical detection system. The optical sensor uses light absorption properties of hemoglobin to measure tissue oxygen saturation and infer compartment pressure, eliminating the need for physical penetration and specialized training while maintaining diagnostic accuracy.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent performs preliminary non-invasive screening using optical sensors before committing to invasive procedures. The system can quickly assess tissue oxygen saturation and identify suspicious areas, allowing clinicians to prioritize cases that truly need invasive confirmation, thereby reducing overall diagnostic time.

Inventive Principle:
Principle #10Preliminary action

4Measurement precision

If needle or catheter insertion method is used to measure ICP, then measurement precision is improved, but object-affected harmful factors worsen due to invasive nature causing additional tissue trauma

Engineering Contradiction:
ImproveICP measurement accuracyVSAvoidtissue trauma
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent replaces the mechanical needle insertion system with an optical detection system. The optical sensor uses light absorption properties of hemoglobin to measure tissue oxygen saturation and infer compartment pressure, eliminating the need for physical penetration and specialized training while maintaining diagnostic accuracy.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent converts the harmful effect of light absorption by deoxygenated hemoglobin into a beneficial diagnostic signal. By measuring the reduced light absorption in ischemic tissue, the system transforms what would be a harmful indicator (oxygen deprivation) into a useful diagnostic marker for compartment syndrome detection.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The apparatus provides a convenient and accurate means for detecting compartment syndrome in field conditions and emergency rooms, enabling timely intervention to prevent tissue damage and disability.

Implementation Method 1

an optical sensor configured to detect oxygen saturation at multiple depths of a subject in contact with the subject contact element. The optical sensor includes a light emitting diode (LED) and multiple photo detectors at corresponding different distances from the LED

Methodology Applied
Scientific EffectLight absorption: Absorption (EM radiation)

Data Source

PatentEP4494547A1Handheld non-invasive compartment syndrome detector
Publication Date: 2025.01.22 UNIV OF MARYLAND
  • EP4494547A1 patent drawingFigure 1
  • EP4494547A1 patent drawingFigure 2A
  • EP4494547A1 patent drawingFigure 2B

AI summary

Techniques for non-invasive detection of compartment syndrome (CS) in a subject, includes an apparatus having a structural body configured to be held in a human hand. The structural body includes a subject contact element that is not in contact with the human hand and is configured to contact but not penetrate a skin layer of a subject. The apparatus also includes an optical sensor configured to detect oxygen saturation at a plurality of depths of a subject in contact with the subject contact element. The optical sensor includes at least one light emitting diode (LED) and multiple photo detectors at corresponding different distances from the LED.