Blood Vessel Optical Fiber Guide Wire with Hydrophilic Coating
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Solution Overview
Problem
Current medical technologies, such as Seldinger artery encheiresis and photodynamic therapy, face limitations in guiding light into and out of blood vessels for diagnosis and treatment, restricting their application due to the inability of traditional guide wires to transmit light and the limited range of photodynamic action.
Innovation Solution
A blood vessel optical fiber guide wire is developed, comprising an optical fiber core wire with a hydrophilic coating and a wrapping layer, allowing light to be guided into and out of the lesion site through the vessel, enhancing compatibility and strength for effective treatment.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Use of energy by moving object
If traditional guide wires are used for blood vessel intervention, then the guide wire can enter the blood vessel and reach the lesion location, but the guide wire cannot transmit light energy for photodynamic therapy
Solution Approach 1:
The guide wire is constructed as a composite structure integrating optical fiber core wire (for light transmission) with metal winding wire (for mechanical strength and guidability). This composite design enables the guide wire to simultaneously perform both guiding functions and light transmission functions that traditional single-material guide wires cannot achieve.
Solution Approach 2:
The guide wire is designed to perform multiple functions: (1) mechanical guidance through the blood vessel to the lesion site, (2) light transmission for photodynamic therapy, and (3) diagnostic imaging capability. This multi-functional design resolves the contradiction by making the guide wire universally applicable for both therapeutic and diagnostic purposes.
2Object-affected harmful factors
If photodynamic therapy is applied to tumors, then less injury and better targeting are achieved, but the treatment range is limited to body surface or large orifices and cannot reach internal lesion locations
Solution Approach 1:
The optical fiber guide wire acts as an intermediary device that bridges the light source (external) and the deep internal lesion site. The optical fiber transmits light through the blood vessel system to reach tumors that are inaccessible by external light sources alone, thereby extending the treatment range to internal locations while maintaining the ease of photodynamic therapy operation.
3Use of energy by moving object
If metal guide wire is used for percutaneous vascular approach, then the guide wire has good strength and guidability, but it cannot transmit light and limits the treatment to chemia and hypoxia mechanisms
Solution Approach 1:
The guide wire combines optical fiber material (for light transmission) with metal winding wire (for strength and guidability). The metal winding wire provides the necessary mechanical properties while the optical fiber core enables light transmission, thus resolving the contradiction between light transmission capability and structural strength.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The optical fiber guide wire enables light to be precisely directed into and out of blood vessels, facilitating both diagnosis and treatment, improving treatment efficacy and reducing resistance within the body.
Implementation Method 1
at least one of optical fiber core wire for transmitting the light
Implementation Method 2
a hydrophilic coating capable of improving compatibility with body liquids and reducing the resistance
Data Source
AI summary
A blood vessel optical fiber guide wire includes at least one of optical fiber core wire, a wire wrapping layer and a hydrophilic coating capable of improving compatibility with body liquids and reducing the resistance. The optical fiber core wire is disposed in a core of the optical fiber guide wire. The wire wrapping layer is formed from at least one of winding wire or winding sheet wrapping outside of the optical fiber core wire. The hydrophilic coating is coated outside of the wire wrapping layer. The optical fiber guide wire may enter a predetermined position in artery blood vessel of human body. The light can be guided into and/or guided out of a location of lesion so as to achieve the photodynamic treatment of diseases such as tumor in vivo. The need to diagnosis and treatment in the field including biology and medical treatment can be met.