Optical Measurement Tuning via Permittivity Sensors

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Solution Overview

Problem

Existing methods for tuning optical measurements in continuously mixed reactors are hindered by the difficulty in maintaining reproducible conditions due to moving components, changes in fluid dynamics, and external influencing factors, leading to inaccurate assessments of the reactor content's form, distribution, and movement state.

Innovation Solution

The method involves using permittivity sensors to detect local permittivity changes within the reactor, which are then used to directly tune optical measurements, independent of process-related changes, by correlating local permittivity with the form, distribution, or movement state of the reactor content, employing capacitive sensors and control units to adjust optical measurements accordingly.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If optical measurements are performed on continuously mixed reactors, then process monitoring capability is improved, but measurement reliability deteriorates due to moving components and changing optical paths

Engineering Contradiction:
Improveprocess monitoring capabilityVSAvoidmeasurement reliability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The system performs preliminary detection of the reactor content's movement state using permittivity sensors before optical measurements are taken. This advance knowledge allows the optical measurement timing and parameters to be pre-adjusted to match the expected liquid state, ensuring reliable measurements despite continuous mixing.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system continuously monitors the movement state of reactor content using permittivity sensors and uses this feedback information to dynamically adjust optical measurement parameters and timing. This closed-loop control ensures that optical measurements are always performed under optimal conditions regardless of mixing state.

Inventive Principle:
Principle #23Feedback

2Productivity

If optical measurements are performed in agitated reactors with continuous mixing, then measurement frequency is improved, but measurement precision deteriorates due to fluctuating liquid distribution

Engineering Contradiction:
Improvemeasurement frequencyVSAvoidoptical measurement precision
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system detects the liquid distribution state in advance using permittivity sensors before optical measurements are executed. This preliminary detection allows selection of optimal measurement moments when liquid distribution is favorable, maintaining high measurement frequency while ensuring precision.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system dynamically adjusts optical measurement parameters based on real-time detection of liquid distribution state. Measurement timing, duration, and parameters are adapted to match the current mixing state, allowing high-frequency measurements without sacrificing precision.

Inventive Principle:
Principle #15Dynamics

3Productivity

If optical measurements are performed in stirred reactors with moving stirrers, then process monitoring capability is improved, but measurement reliability deteriorates due to stirrer interference in optical path

Engineering Contradiction:
Improveprocess monitoring capabilityVSAvoidmeasurement reliability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The system detects the position and movement state of reactor content relative to stirrers before optical measurements are taken. This advance detection allows timing of optical measurements to coincide with moments when the optical path is clear of stirrer interference.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system performs optical measurements periodically at intervals synchronized with the stirrer rotation cycle, detecting optimal measurement windows when the optical path is unobstructed. This periodic measurement strategy maintains monitoring capability while avoiding stirrer interference.

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach provides more accurate and robust optical measurements by directly detecting the reactor content's state, reducing susceptibility to errors from external factors and fluid dynamic changes, and allowing for real-time correction of optical data.

Implementation Method 1

a local permittivity of the reactor content is detected by at least one permittivity sensor

Methodology Applied
Scientific EffectPermittivity detection: Dielectric Permittivity

Implementation Method 2

optical methods, such as scattered light measurements, absorption measurements, or fluorescence measurements

Methodology Applied
Scientific EffectOptical measurement: Absorption Spectroscopy

Implementation Method 3

fluorescence measurements

Methodology Applied
Scientific EffectFluorescence: Fluorescence

Data Source

PatentUS10386294B2Method and device for tuning optical measurements on continuously mixed reactors
Publication Date: 2019.08.20 AQUILA BIOLABS
  • US10386294B2 patent drawing
  • US10386294B2 patent drawing
  • US10386294B2 patent drawing

AI summary

A method for tuning optical measurements on continuously mixed reactors, wherein a content of the reactor has at least one optically detectable measured variable, which is carried out by at least one optical measuring arrangement, wherein at least one optical measurement is tuned to a form, distribution, or movement state of at least one phase of the reactor content, wherein mixing the reactor content causes local changes in the permittivity within the reactor, which is detected at at least one location having a known distance from the at least one optical measuring arrangement to be tuned based on a permittivity signal, and wherein the detected permittivity signal of at least one location having a known distance from the at least one optical measuring arrangement to be tuned is used to tune at least one optical measurement to the form, distribution, or movement state of the reactor content.