Noninvasive Optical Physiological Measurement with Motion Artifact Correction

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Solution Overview

Problem

Current noninvasive optical systems for measuring physiological properties in tissue, such as oxygenation and heart rate, are limited by motion and orientation artifacts, requiring subjects to remain still or follow specific movements, making real-time monitoring in everyday conditions challenging, especially for distinguishing between venous and arterial blood parameters.

Innovation Solution

A system combining an optical sensor with a mechanical sensor, utilizing light emitters that emit multiple wavelengths and an accelerometer to differentiate between venous and arterial blood parameters by leveraging the distinct responses of venous and arterial vascular systems to motion and orientation changes, allowing for the evaluation of venous blood properties during regular activities.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If noninvasive optical systems are used to measure physiological properties in tissue, then oxygenation and heart rate can be evaluated, but motion and orientation artifacts degrade measurement quality

Engineering Contradiction:
Improvemeasurement qualityVSAvoidmotion and orientation artifacts
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent introduces a mechanical sensor (accelerometer) as an intermediary device that detects motion and orientation changes. This sensor acts as a mediator between the optical measurement system and the motion artifacts, providing data that is used to identify and correct artifact-contaminated measurements, thereby improving overall measurement quality without requiring the subject to remain still

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system implements feedback by continuously monitoring motion parameters with the accelerometer and using this information to adjust or correct the optical measurements in real-time. The processor uses the mechanical sensor data to identify when motion artifacts are present and applies corrections to maintain measurement accuracy during movement

Inventive Principle:
Principle #23Feedback

2Measurement precision

If subjects are required to remain still during evaluation, then measurement quality improves, but real-time monitoring during everyday activities becomes impossible

Engineering Contradiction:
Improvemeasurement qualityVSAvoidreal-time monitoring capability
Core Design Contradiction:
Measurement precisionVSAdaptability or versatility

Solution Approach 1:

The patent transitions from a static measurement approach (requiring subjects to remain still) to a dynamic approach that adapts to movement. By incorporating motion sensors and using algorithms that can distinguish between physiological signals and motion artifacts, the system maintains measurement quality while allowing subjects to move naturally, enabling real-time monitoring during everyday activities

Inventive Principle:
Principle #15Dynamics

3Measurement precision

If mechanical sensors are used to detect motion, then motion artifacts can be identified, but the system complexity increases

Engineering Contradiction:
Improvemotion artifact detectionVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines the optical sensor system with a mechanical motion sensor (accelerometer) into an integrated measurement device. By merging these different sensing modalities, the system leverages the strengths of each sensor type - the optical sensor for physiological measurements and the mechanical sensor for motion detection - while sharing processing resources and data fusion algorithms, thereby managing complexity through integration rather than separate systems

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables accurate, real-time monitoring of venous and arterial blood properties without the need for subjects to remain still, providing reliable measurements of oxygenation and heart rate variability even during movement and changes in position, enhancing the precision and convenience of physiological property assessment.

Implementation Method 1

a light emitter (46.1-46.3) capable of emitting light of at least two different wavelengths

Methodology Applied
Scientific EffectLight transmission through tissue: Absorption (EM radiation)

Data Source

PatentEP2768391B1Method for noninvasive optical measurements of physiological properties in tissue
Publication Date: 2019.05.01 BIOVOTION
  • EP2768391B1 patent drawingFigure 1~2
  • EP2768391B1 patent drawingFigure 3~4
  • EP2768391B1 patent drawingFigure 5~10

AI summary

Embodiments of the present invention comprise systems and methods for noninvasive measurements of physiological properties of tissue. The system comprises a light emitter, an optical detector, a mechanical sensor and a processor. The light emitter is capable of emitting light of at least two different wavelengths and comprises at least one light source. The processor is capable of evaluating physiological properties of the tissues from measurements of the optical and the mechanical sensor. More precisely, the processor is capable of evaluating physiological properties of venous blood by using data measured by the mechanical sensor and the optical detector. For example, the oxygenation of venous blood can be measured. Furthermore, the systems can optionally comprise a light emitter which emits three wavelengths and/or the light emitter and the optical detector are arranged in reflection geometry and are located at a distance of at most 10 mm from each other.