Optical Probe With Modulator For Selective Nerve Stimulation

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Solution Overview

Problem

Current optical probes for stimulating or suppressing nerve cells in the brain or spinal cord lack the ability to selectively target specific areas and efficiently extract electrical signals, limiting their effectiveness in research and treatment applications.

Innovation Solution

An optical probe is designed with a light source, waveguides, electrodes, and a modulator that includes rotating mirrors or light condensers to selectively transmit optical signals to specific waveguides, allowing for precise stimulation of nerve cells and simultaneous electrical signal recording.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If a single optical probe is used to stimulate nerve cells, then the device structure is simple, but the ability to selectively target specific areas is lost

Engineering Contradiction:
Improveselective targeting capabilityVSAvoiddevice structure
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The optical probe is divided into multiple independent waveguides (first waveguide, second waveguide, etc.), each capable of independently transmitting optical signals to different spatial locations. This segmentation allows selective stimulation of different nerve cell areas while maintaining a relatively simple integrated probe structure.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces spatial dimensionality by arranging multiple waveguides in different spatial orientations and positions. Each waveguide can be directed toward different target areas, adding a spatial selection dimension to the optical stimulation system without significantly increasing overall device complexity.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Measurement precision

If multiple waveguides are used to target specific areas, then the selective stimulation capability is improved, but the device complexity increases

Engineering Contradiction:
Improvetargeting precisionVSAvoiddevice structure
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

Multiple waveguides are merged into a single integrated optical probe structure, sharing common components such as the light source, modulator, and housing. This combining approach enables precise multi-point targeting while avoiding the complexity of multiple separate devices.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The optical probe is designed as a multi-functional device where a single structure performs multiple functions: generating optical signals, modulating them, transmitting through multiple waveguides to different targets, and recording electrical signals. This universality reduces overall system complexity while maintaining high targeting precision.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Adaptability or versatility

If optical signals are transmitted to multiple waveguides simultaneously, then the coverage area is expanded, but the light transmission efficiency decreases

Engineering Contradiction:
Improvecoverage areaVSAvoidlight transmission efficiency
Core Design Contradiction:
Adaptability or versatilityVSLoss of energy

Solution Approach 1:

The modulator dynamically controls the optical signal transmission to different waveguides based on experimental requirements. By dynamically routing optical signals only to the waveguides that need active stimulation at any given moment, the system expands coverage area while minimizing energy loss through selective activation.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The modulator automatically directs optical signals to the appropriate waveguides without requiring external intervention for each stimulation event. This self-service capability ensures efficient light transmission by inherently routing signals only where needed, maintaining high transmission efficiency while providing broad coverage capability.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The optical probe enables selective stimulation of nerve cells and efficient extraction of electrical signals, enhancing research and treatment capabilities by improving light transmission efficiency and targeting precision.

Implementation Method 1

a light source configured to generate an optical signal

Methodology Applied
Scientific EffectOptical signal generation: Light

Implementation Method 2

a plurality of waveguides configured to guide the optical signal to a target

Methodology Applied
Scientific EffectWaveguide: Waveguide (optics)

Implementation Method 3

a mirror that rotates around a first direction intersecting with a longitudinal direction of the plurality of waveguides and reflects the optical signal to the at least one target waveguide

Methodology Applied
Scientific EffectReflection: Reflection

Implementation Method 4

a light condensing element that linearly moves in a first direction intersecting with a longitudinal direction of the plurality of the waveguides or in a second direction intersecting with the longitudinal direction and the first direction for condensing the optical signal to the at least one target waveguide

Methodology Applied
Scientific EffectLight condensing: Lens

Implementation Method 5

a plurality of electrodes configured to record an electrical signal generated by the target

Methodology Applied
Scientific EffectElectrical signal detection: Photoelectric Effect

Data Source

PatentUS12128248B2Optical probe
Publication Date: 2024.10.29 EWHA UNIV IND COLLABORATION FOUND
  • US12128248B2 patent drawing
  • US12128248B2 patent drawing
  • US12128248B2 patent drawing

AI summary

An optical probe includes a light source configured to generate an optical signal, a plurality of waveguides configured to guide the optical signal to a target, a plurality of electrodes configured to record an electrical signal generated by the target, and a modulator configured to transmit the optical signal of the light source to at least one target waveguide from among the plurality of waveguides.