Optical Sensor Adaptive Mode Selection for Tissue Scattering

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing optical devices for detecting properties of target tissues in biological environments face challenges in maximizing sensitivity due to varying properties of intervening tissues, such as scattering coefficients and depths, which affect the accuracy and efficiency of non-invasive measurements.

Innovation Solution

The method involves detecting properties of intervening tissues and selecting operational modes for optical devices to optimize sensitivity, by adjusting parameters like beam width, field of view, and illumination intensity based on detected tissue properties, using calibration curves and computational models to determine the most effective configuration for maximum sensitivity detection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a fixed operational mode is used for optical devices, then device complexity is reduced, but measurement precision deteriorates due to varying tissue properties

Engineering Contradiction:
ImprovesensitivityVSAvoidoperational mode selection
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent implements dynamic operational mode selection by detecting tissue properties (scattering coefficient, depth) and automatically adjusting optical device parameters (beam width, field of view, illumination intensity) to maximize sensitivity for each specific tissue configuration, resolving the contradiction between fixed simplicity and variable precision

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system changes multiple operational parameters simultaneously based on detected tissue properties: beam width is adjusted to match scattering characteristics, field of view is optimized for detected depth, and illumination intensity is modulated according to tissue optical properties, achieving maximum sensitivity across varying tissue conditions

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If operational modes are optimized for specific tissue properties, then measurement precision improves, but ease of operation deteriorates

Engineering Contradiction:
Improvedetection sensitivityVSAvoidoperational complexity
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The optical device performs self-optimization by automatically detecting its own operational environment (tissue scattering coefficient and depth) and selecting the appropriate operational mode without user intervention, making complex adaptive operation as simple as initiating a measurement

Inventive Principle:
Principle #25Self-service

3Measurement precision

If tissue properties are detected and operational modes are selected dynamically, then sensitivity is maximized, but loss of time increases due to additional detection and selection steps

Engineering Contradiction:
ImprovesensitivityVSAvoidmeasurement preparation time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

Tissue property detection is performed as a preliminary step before the actual measurement, allowing the system to pre-select the optimal operational mode and avoid suboptimal measurements, with the detection itself being rapid and non-intrusive

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The tissue detection and sensitivity optimization processes are merged into a single integrated workflow where detection data immediately informs operational mode selection, eliminating separate preparation steps and minimizing time loss

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the accuracy and efficiency of non-invasive detection of target tissue properties by optimizing the operational mode of optical devices in response to varying biological environment conditions, improving sensitivity and reliability of measurements.

Implementation Method 1

emit light through the external body surface and the intervening tissue to illuminate the target tissue

Methodology Applied
Scientific EffectLight transmission through tissue: Absorption (EM radiation)

Implementation Method 2

varying properties of intervening tissues, such as scattering coefficients

Methodology Applied
Scientific EffectLight scattering in tissue: Scattering

Implementation Method 3

detecting light emitted from the target tissue through the intervening tissue and the external body surface

Methodology Applied
Scientific EffectLight detection: Photoelectric Effect

Data Source

PatentUS10499839B1Optimized biophotonic sensors
Publication Date: 2019.12.10 VERILY HEALTH INC
  • US10499839B1 patent drawing
  • US10499839B1 patent drawing
  • US10499839B1 patent drawing

AI summary

Methods and devices are provided for optically interrogating subsurface tissues of a body. Optical interrogation includes illumination of a target tissue through an external body surface and detection of light emitted in response to the illumination. Parameters of such optical interrogation are controlled according to operational modes that are selected to maximize detector sensitivity to a target property of the target subsurface tissues. Operational modes are selected based on detected properties of the target tissue and of intervening tissues (e.g., thickness of intervening tissues between the target tissue and an external body surface) between the target tissue and an interrogating optical device. Operational modes can be determined based on simulated optical interrogation of subsurface tissue across a range of optical detector configurations and tissue conditions. Operational modes can include calibration curves specifying optical interrogation parameters based on intervening tissue properties.