Optical Sensor Delivery System for Irregular Wound Mapping
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Solution Overview
Problem
Current treatments for burns and large body surface area wounds are inadequate due to the need for multiple surgical procedures, inability to cover irregular wounds, and lack of precision in delivering cells, leading to suboptimal healing and increased morbidity.
Innovation Solution
A delivery system that uses a control module to generate a map of the patient's bodily surface and operate a dispensing system to precisely deliver cells and compositions based on scanned data, incorporating a three-dimensional scanner and printheads to create tissue layers that match the wound's geometry.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If standard-sized skin substitutes are produced through large-scale manufacturing processes, then production efficiency is improved, but the ability to cover irregular wounds deteriorates
Solution Approach 1:
The skin substitute is divided into multiple standard-sized modules that can be individually produced through large-scale manufacturing. Each module contains living skin cells on a biocompatible substrate. These modular units can then be assembled and customized to match irregular wound geometries, combining mass production efficiency with adaptability to complex wound shapes.
Solution Approach 2:
The invention transitions from producing single fixed-size skin substitutes to creating a library of standard-sized modules that can be arranged in two-dimensional patterns. This modular approach allows the treatment area to be scaled and shaped according to the specific wound geometry, enabling coverage of irregular surfaces while maintaining standardized manufacturing processes for each module.
2Reliability
If multiple surgical procedures are used to treat large body surface area burns, then treatment thoroughness is improved, but treatment time and patient morbidity worsen
Solution Approach 1:
Multiple skin substitute modules are prepared in advance through standardized manufacturing processes before the surgical procedure. The patient's wound area is mapped and measured prior to surgery, allowing pre-planning of module arrangement. During surgery, the pre-prepared modules are simply assembled and implanted, eliminating the need for multiple procedures while maintaining comprehensive coverage.
Solution Approach 2:
The invention combines multiple skin substitute modules into a single comprehensive treatment procedure. Rather than performing separate surgeries for different body areas or sequential grafting, all necessary modules are prepared and implanted during one surgical session, merging what would traditionally require multiple procedures into a single intervention.
3Speed
If cell spraying technology is used to deliver cells, then delivery speed is improved, but delivery precision deteriorates
Solution Approach 1:
The invention replaces the mechanical spraying system with a controlled placement system. Instead of relying on aerosolized cell delivery, the skin substitutes are prepared with cells already organized on structured biocompatible substrates. During implantation, these pre-organized modules are placed directly onto the wound bed, ensuring precise cell positioning while maintaining efficient delivery through standardized surgical protocols.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This system enables precise, single-procedure delivery of cells and compositions to irregular wounds, promoting effective healing, reducing morbidity, and potentially offering indefinite shelf life and minimal storage requirements.
Implementation Method 1
an optical sensor configured to detect data used to create a map of a patient bodily surface
Data Source
AI summary
Provided herein is a delivery system, including: (a) an optical sensor configured to detect data to create a map of a patient bodily surface; and (b) a dispenser operatively associated with the optical sensor and configured to deliver compositions (optionally including cells) to the patient bodily surface based upon the data or map. Methods of forming a tissue on a patient bodily surface of a patient in need thereof are also provided, as are methods, systems and computer program products useful for processing patient bodily surface data.