Optical Signal Detection via Spatial Separation on Single Detector

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Solution Overview

Problem

Current optical signal detection systems are complex and costly, often failing to achieve high sensitivity due to multiple manipulations and signal losses, particularly when dealing with weak or low-concentration optical signals from chemical and biochemical reactions.

Innovation Solution

The system employs a confined source of optical signals with distinct characteristics, such as wavelength, which are spatially separated and directed to different locations on a single optical detector using a simplified optical train with modular components like prisms or gratings, reducing complexity and signal loss.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If multiple optical signals are detected using conventional systems with multiple manipulations, then signal separation and detection are achieved, but system complexity and cost increase, and sensitivity decreases

Engineering Contradiction:
Improvesignal detection sensitivityVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines multiple optical signal detection paths into a single integrated optical train that directs different wavelength signals to different locations on one detector. This merging of detection functions reduces the number of separate systems needed, thereby reducing overall system complexity while maintaining the ability to detect multiple signals with high sensitivity

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The optical train is designed with multi-functionality to handle multiple optical signals of different wavelengths through a single system. By incorporating wavelength-dependent beam splitting and a single detector capable of spatially resolving different wavelengths, the system achieves universal detection capability across multiple signal types without requiring separate specialized systems for each wavelength

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Measurement precision

If multiple optical signals undergo multiple manipulations for separation and detection, then signal identification is achieved, but signal loss increases and sensitivity decreases

Engineering Contradiction:
Improvesignal detection sensitivityVSAvoidsignal loss
Core Design Contradiction:
Measurement precisionVSLoss of energy

Solution Approach 1:

The optical train maintains continuous optical paths from the light source through the beam splitting elements to the detector without introducing discrete manipulation steps that would cause signal loss. The wavelength-dependent beam splitting occurs continuously along the optical path rather than through multiple discrete manipulation stages, preserving signal intensity and minimizing loss while achieving complete separation and detection of all optical signals

Inventive Principle:
Principle #20Continuity of useful action

3Measurement precision

If conventional systems are used to detect multiple optical signals, then signal separation is achieved, but cost increases

Engineering Contradiction:
Improvesignal separation capabilityVSAvoidsystem cost
Core Design Contradiction:
Measurement precisionVSEase of manufacture

Solution Approach 1:

The patent merges multiple detection functions into a single optical train with one detector, eliminating the need for multiple separate detection systems. This consolidation reduces the overall cost of the system while maintaining full capability to separate and detect multiple optical signals of different wavelengths

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for efficient and cost-effective detection of multiple optical signals with increased sensitivity, particularly useful in low-light applications like single molecule reactions, by minimizing signal manipulation and maintaining the entire spectrum for detection.

Implementation Method 1

passing the signals through an optical train that transmits the first and second optical signals in divergent paths

Methodology Applied
Scientific EffectRefraction: Refraction

Implementation Method 2

spatially separating the plurality of different optical signals and directing them to discrete locations on one optical detector

Methodology Applied
Scientific EffectDiffraction: Diffraction

Data Source

PatentUS7805081B2Methods and systems for monitoring multiple optical signals from a single source
Publication Date: 2010.09.28 PACIFIC BIOSCIENCES OF CALIFORNIA INC
  • US7805081B2 patent drawing
  • US7805081B2 patent drawing
  • US7805081B2 patent drawing

AI summary

Methods and systems for monitoring a plurality of different optical signals from a single source of such signals, where each such different optical signal is spatially separated from other such signals and directed to different detectors or locations upon a single detector, which direction is generally accomplished through the use of a small number of optical components and/or manipulations.