Implantable Optical Stimulator for Real-Time Organ Modulation

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Solution Overview

Problem

Current medical devices implanted in humans cannot control organ operation across a range of levels based on real-time data, lacking the ability to analyze and respond to dynamic organ activity using artificial intelligence.

Innovation Solution

An implantable device with a sensor, stimulator, and transceiver that detects real-time activity data from an organ, transmits it to an external device for analysis, and adjusts the illumination of light components to modulate organ function, utilizing an AI engine to generate stimulation parameters for graded activation or inhibition of nerve clusters like the stellate ganglia.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If permanent activation or inhibition of organ operation is implemented using current implantable devices, then the organ function can be controlled at fixed levels, but the device cannot adapt to real-time organ activity changes and lacks graded control capability

Engineering Contradiction:
Improveadaptability to real-time organ activityVSAvoiddevice complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The implantable device transitions from static permanent activation/inhibition to dynamic real-time control by continuously monitoring organ activity through sensors and adjusting light component illumination accordingly. The device adapts its stimulation parameters based on real-time detected organ activity, enabling graded control across multiple levels rather than fixed binary states.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The device incorporates a feedback loop where sensors detect real-time organ activity data, which is then processed by an AI engine to determine appropriate stimulation parameters. The light components are controlled based on this feedback, creating a closed-loop system that continuously adjusts organ modulation based on actual organ state rather than predetermined fixed settings.

Inventive Principle:
Principle #23Feedback

2Extent of automation

If current implantable devices are used to control organ operation, then surgical embedding is possible, but real-time data gathering and AI-based control adjustment cannot be achieved

Engineering Contradiction:
Improveautomation of real-time control adjustmentVSAvoiddevice complexity
Core Design Contradiction:
Extent of automationVSDevice complexity

Solution Approach 1:

The device performs self-monitoring and self-adjustment through integrated sensors that detect organ activity and an AI engine that automatically processes this data and controls light component illumination. The system serves itself by autonomously making control decisions based on real-time feedback without requiring external intervention, achieving automated graded control of organ function.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The implantable device integrates multiple functions into a single system: sensing organ activity, processing data through AI algorithms, and delivering optical stimulation. This multi-functional integration enables the device to both monitor and control organ operation autonomously, combining detection and actuation capabilities in one implantable unit.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Measurement precision

If light components are used to stimulate nerve clusters, then organ operation can be modulated, but precise control across a range of levels based on real-time data requires advanced AI processing

Engineering Contradiction:
Improveprecision of organ function modulationVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The device achieves precise control by dynamically changing multiple parameters of light component illumination including intensity, duration, frequency, and wavelength. The AI engine processes real-time organ activity data and adjusts these illumination parameters to achieve desired levels of organ modulation, enabling fine-grained control across a continuous range rather than discrete fixed levels.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The device uses multiple separate light components corresponding to different wavelengths that can be independently controlled. This segmentation allows the AI engine to selectively activate specific wavelength components based on the type and intensity of organ activity detected, enabling precise targeted modulation of different nerve cluster responses through wavelength-specific stimulation.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables precise modulation of organ function to prevent conditions such as cardiac arrest and optimize cardiac operation by reducing free radicals and sympathetic nervous system activity, while avoiding the drawbacks of permanent activation or inhibition.

Implementation Method 1

a sensor configured to detect, in real time, activity data from a tissue cluster of an organ

Methodology Applied
Scientific EffectSensor detection:

Implementation Method 2

a stimulator including a plurality of light components corresponding to at least a first wavelength and a second wavelength

Methodology Applied
Scientific EffectLight emission: Light Emitting Diode

Data Source

PatentUS20230338744A1Implantable device for organ operation modulation
Publication Date: 2023.10.26 VANDERBILT UNIV
  • US20230338744A1 patent drawing
  • US20230338744A1 patent drawing
  • US20230338744A1 patent drawing

AI summary

A system for modulating operation of an organ in real time by controlling illumination of one or more light components is provided. The system includes an external device comprising a processing unit and a power supply configured to transmit stimulation parameters, a wireless implantable device comprising, a sensor configured to detect, in real time, activity data from a tissue cluster of an organ, a stimulator including a plurality of light components corresponding to at least a first wavelength and a second wavelength and a flexible elastomer coupled to the plurality of light components, and a transceiver configured to transmit the activity data to the external device, wherein the stimulator is configured to illuminate, based on the stimulation parameters, one of the plurality of light components coupled to the flexible elastomer, wherein the processing unit is configured to update the stimulation parameters based on the activity data.