Optical Trap Calibration via Nanoparticle Imaging and Electric Field Variation

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Solution Overview

Problem

Current calibration methods for vacuum optical traps are error-prone and indirect, requiring fast and accurate switching control of light sources and external force fields, which complicates the calibration of nano-scale sensing particles.

Innovation Solution

An optical trap calibration apparatus and method using optical imaging of nanoparticles, which includes a first laser, a second laser, a vacuum chamber, an objective lens, an electric field imposing unit, and an imager, allowing for precise calibration of mechanical quantities by varying electric fields and directly imaging particle positions and behaviors.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If the current calibration method using free accelerated movement is employed, then the calibration can be performed with existing equipment, but the measurement precision and reliability are poor due to multiple error sources and indirect testing

Engineering Contradiction:
Improvecalibration precisionVSAvoidcontrol system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces the indirect mechanical calibration method (measuring free accelerated movement) with a direct optical imaging method. By using a camera to directly image the nanoparticle position and combining it with electric field variation, the system eliminates the need for complex light source switching and force field control, thereby improving measurement precision while reducing device complexity.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces an electric field as an intermediary to establish a known force on the charged nanoparticle. By applying a controlled electric field to a charged particle, the force can be precisely calculated (F=qE), providing a reliable reference for calibration without requiring complex mechanical acceleration measurements.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If fast and accurate switching control of light source and external force field is implemented, then the calibration process can be completed, but the device complexity and operation difficulty increase significantly

Engineering Contradiction:
Improvecalibration efficiencyVSAvoidoperation simplicity
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The patent replaces the complex switching control of light sources and force fields with a continuous optical imaging system. The camera continuously captures particle position, and the electric field is applied steadily during measurement, eliminating the need for rapid switching operations and simplifying the calibration process.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system uses the nanoparticle's own charge property to generate the calibration force through the electric field, eliminating the need for external force field switching. The optical imaging system continuously monitors the particle position without requiring light source switching, making the system self-sufficient and easier to operate.

Inventive Principle:
Principle #25Self-service

3Reliability

If indirect calibration through free accelerated movement is used, then the existing optical trap system can be utilized, but the reliability of calibration results is poor due to multiple error sources

Engineering Contradiction:
Improvecalibration reliabilityVSAvoidsystem implementation complexity
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent replaces the unreliable indirect mechanical measurement (free accelerated movement) with a direct optical position measurement combined with electric field force calculation. This substitution provides more reliable calibration results by directly observing particle displacement under a known electric force, avoiding the accumulation of errors from timing and acceleration measurements.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The electric field serves as a reliable intermediary that provides a precisely calculable force (F=qE) on the charged nanoparticle. This known force, combined with direct optical position measurement, creates a reliable calibration method that avoids the multiple error sources inherent in measuring free accelerated movement.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach promotes the development and application of vacuum optical trap sensing technology by providing precise calibration and direct monitoring of particle dynamics, enhancing capture efficiency and enabling the detection of particle properties and behaviors.

Implementation Method 1

the first laser emitting capture laser with a wavelength of λ1, the capture laser entering the vacuum chamber after passing through the beam splitter, and the objective lens performing focusing to form an optical potential well, so as to trap the nanoparticle in the optical potential well

Methodology Applied
Scientific EffectOptical tweezers: Optical Tweezers

Implementation Method 2

the second laser emitting flat-top laser with a wavelength of λ2 to irradiate the optical potential well

Methodology Applied
Scientific EffectLight scattering: Scattering

Implementation Method 3

the electric field imposing unit can generate parallel electric fields in three directions of x, y and z

Methodology Applied
Scientific EffectElectric field force: Electric Field

Implementation Method 4

applying no electric field, and after the particle is cooled, recording scattered light distribution on the image plane of the imager

Methodology Applied
Scientific EffectLorentz force: Lorentz Force

Data Source

PatentUS12189110B2Optical trap calibration apparatus and method based on variation of electric field by optical imaging of nanoparticle
Publication Date: 2025.01.07 ZHEJIANG LAB
  • US12189110B2 patent drawing
  • US12189110B2 patent drawing
  • US12189110B2 patent drawing

AI summary

Disclosed is an optical trap calibration apparatus and method based on variation of electric field by optical imaging of a nanoparticle. By means of a direct optical imaging method, a linear nanoparticle equilibrium position displacement under the action of a constant electric field is measured to realize calibration, thereby avoiding the introduction of error signals, and improving the reliability of differential calibration. The specific calibration method and apparatus of the present invention are not only suitable for calibration of electric field quantity, but also suitable for the calibration of other magnetic forces and the like. By means of the accurate calibration of mechanical quantity in the present invention, the development and application of the vacuum optical trap sensing technology can be promoted.