Optofluidic Laser Surface Gain Interface

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Solution Overview

Problem

Previous optofluidic lasers face issues such as high gain material requirements, low detection sensitivity, background fluorescence, limited biocompatibility, low Q-factors, and difficulties in reusability and mass production for high-throughput biosensing applications.

Innovation Solution

The development of optofluidic lasers with a layer of gain material confined to a liquid-liquid interface between immiscible liquids, using a small quantity of self-assembling amphiphilic molecules, which form microdroplets that define optical cavities with high Q-factors, enabling customizable and biocompatible devices for enhanced sensitivity and reconfigurability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If bulk solution containing gain material is used, then laser emission is achieved, but detection sensitivity deteriorates and background fluorescence increases

Engineering Contradiction:
Improvedetection sensitivityVSAvoidbackground fluorescence
Core Design Contradiction:
Measurement precisionVSObject-generated harmful factors

Solution Approach 1:

The patent extracts the gain material from the bulk solution and confines it to a monolayer at the liquid-liquid interface. This extraction removes the harmful background fluorescence from the bulk while preserving the lasing function at the interface where the optical cavity is located.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The gain material is concentrated at the specific location of the liquid-liquid interface rather than being distributed throughout the bulk solution. This local concentration creates a high-quality gain region exactly where the optical cavity modes are confined, improving both sensitivity and reducing background noise.

Inventive Principle:
Principle #3Local quality

2Measurement precision

If large quantity of gain material is used in bulk solution, then laser emission is achieved, but detection sensitivity is lowered

Engineering Contradiction:
Improvedetection sensitivityVSAvoidgain material quantity
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The patent extracts the gain material from bulk distribution and concentrates it into a monolayer at the interface, dramatically reducing the total quantity required while maintaining or improving detection sensitivity through localized high-concentration gain at the cavity region.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The system uses a composite structure of two immiscible liquids with an amphiphilic gain material that self-assembles at their interface. This composite arrangement creates a unique monolayer configuration that achieves lasing with minimal material while maximizing sensitivity.

Inventive Principle:
Principle #40Composite materials

3Adaptability or versatility

If conventional optofluidic laser structure is used, then laser operation is achieved, but biocompatibility is limited

Engineering Contradiction:
ImprovebiocompatibilityVSAvoidlaser operation reliability
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The patent changes the fundamental parameter of the gain medium from bulk solution to interfacial monolayer, and uses aqueous-compatible amphiphilic molecules that self-assemble at the liquid-liquid interface. This enables biocompatible aqueous environments while maintaining reliable lasing operation through the high-Q optical cavity.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach reduces background fluorescence, improves detection sensitivity, allows for biocompatibility, and enables high-throughput biosensing with customizable and reusable optofluidic lasers, supporting whispering gallery modes and efficient lasing operations.

Implementation Method 1

optofluidic lasers with surface gain and methods of making and using the same

Methodology Applied
Scientific EffectLasing: Laser

Implementation Method 2

supporting whispering gallery modes and efficient lasing operations

Methodology Applied
Scientific EffectWhispering gallery modes: Resonance

Implementation Method 3

a layer of gain material disposed at and/or confined to the liquid-liquid interface

Methodology Applied
Scientific EffectSelf-assembly: Self-Assembly

Implementation Method 4

use small quantities (e.g., a single monolayer) of self-assembling gain material

Methodology Applied
Scientific EffectAmphiphilic molecule assembly: Amphiphiles

Implementation Method 5

microdroplets that define optical cavities with high Q-factors

Methodology Applied
Scientific EffectTotal internal reflection: Total Internal Reflection

Data Source

PatentUS10124331B2Optofluidic lasers with surface gain and methods of making and using the same
Publication Date: 2018.11.13 BOARD OF RGT THE UNIV OF TEXAS SYST
  • US10124331B2 patent drawing
  • US10124331B2 patent drawing
  • US10124331B2 patent drawing

AI summary

In one aspect, optofluidic lasers are described herein. In some embodiments, an optofluidic laser described herein comprises a first liquid having a first refractive index, a second liquid having a second refractive index that is different than the first refractive index, and a liquid-liquid interface defined by the first and second liquids and disposed between the first and second liquids. Moreover, the first and second liquids are immiscible. Additionally, the optofluidic laser further comprises a layer of gain material disposed at the liquid-liquid interface between the first and second liquids.