Oral Herbal Composition for Bladder Function and Urination Control

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Solution Overview

Problem

There is a need for compositions and methods to improve and maintain bladder function, reduce frequency of urination, and maintain bladder control, particularly in individuals with conditions such as diabetic neuropathy, pelvic arterial insufficiency, and neurological disorders.

Innovation Solution

An oral composition comprising extracts like Rehmanniae radix, Achyranthis radix, Corni Officinalis, Paeonis Suffruticosa, Alisma rhizoma, Dioscorea Villosa, Plantaginis semen, hoelen, Cinnamon cortex, and Piper nigrum, potentially combined with pharmaceutically acceptable excipients, administered to promote bladder function and circulation, and administered multiple times a day for several weeks.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional treatments are used for bladder dysfunction, then some symptoms may be temporarily relieved, but the underlying causes such as poor circulation and nerve damage remain unaddressed

Engineering Contradiction:
Improvebladder function improvementVSAvoidaddressing underlying causes
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines multiple herbal extracts with complementary functions into a single composition. The formula integrates blood-flow enhancing herbs (Achyranthes bidentata, Cinnamon cassia), nerve-regenerating herbs (Rehmannia glutinosa, Cornus officinalis), and bladder-regulating herbs (Alisma orientalis, Plantago asiatica) to simultaneously address circulation, nerve function, and bladder control in one unified treatment

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The herbal composition is designed to perform multiple functions: improving blood circulation to the bladder, regenerating damaged nerves, reducing inflammation, and directly regulating bladder muscle function. This multi-functional approach allows a single composition to address various underlying causes of bladder dysfunction simultaneously

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If high doses of single-herb extracts are used, then potency for specific functions increases, but side effects and toxicity risks increase

Engineering Contradiction:
Improvetherapeutic effectVSAvoidside effects and toxicity
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent uses standardized extracts with controlled concentrations of active compounds from each herb. Rather than using crude extracts or high-dose single herb preparations, the formula employs standardized extracts at optimized doses that provide therapeutic benefits while minimizing toxicity. Each herb contributes specific properties in balanced proportions

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The composition uses a composite of multiple herbal extracts where the synergistic interactions between different herbs enhance therapeutic effects while reducing individual herb toxicity. The combination creates a balanced formulation where herbs with potential side effects are counterbalanced by other herbs in the formula

Inventive Principle:
Principle #40Composite materials

3Speed

If Western pharmaceutical treatments are used, then rapid symptom relief may be achieved, but long-term safety and addression of root causes are compromised

Engineering Contradiction:
Improvesymptom relief speedVSAvoidlong-term safety and efficacy
Core Design Contradiction:
SpeedVSReliability

Solution Approach 1:

The herbal composition addresses the root causes of bladder dysfunction before symptoms fully manifest or worsen. By improving blood circulation and regenerating nerves early in the disease process, the treatment prevents progression to more severe conditions that would require aggressive pharmaceutical intervention

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The formula provides continuous therapeutic action through its multi-component design. Different herbs in the formula act at different stages of the pathological process, ensuring continuous benefit from circulation improvement to nerve regeneration to bladder function normalization, maintaining therapeutic pressure without the peaks and valleys of single-dose pharmaceuticals

Inventive Principle:
Principle #20Continuity of useful action

Data Source

PatentUS11534474B1Oral compositions for bladder regulation and uses thereof
Publication Date: 2022.12.27 AYTU BIOPHARMA INC

AI summary

Oral compositions for supporting bladder function, reduce frequency of urination, and/or improve or maintain bladder control, suitable for oral administration, are described. Methods of use and uses are described, which include the step of administering an effective amount of the oral compositions to supporting bladder function, reduce frequency of urination, and/or improve or maintain bladder control.