Oral Care Composition Stabilization via Pyrophosphate and Gum Ratios
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Solution Overview
Problem
Dentifrice compositions containing chelating agents like tetrasodium pyrophosphate (TSPP) and tetrapotassium pyrophosphate (TKPP) often exhibit phase separation when combined with certain thickening gum systems, leading to metallic taste and astringency issues and reduced stability.
Innovation Solution
An oral care composition comprising 0.5 wt % to 1.5 wt % pyrophosphate compounds and 1.25 wt % to 1.6 wt % thickening gums, along with a metal ion source, is formulated to reduce or prevent phase separation, with specific concentrations of pyrophosphate and gum combinations that enhance stability while maintaining taste and mouthfeel.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If chelating agents like TSPP and TKPP are used to reduce metallic taste and astringency, then taste quality is improved, but phase separation occurs with certain thickening gum systems
Solution Approach 1:
The patent uses a specific thickening gum system comprising carboxymethyl cellulose (0.8-1.2 wt%) and xanthan gum (0.4-0.6 wt%) as an intermediary between the chelating agents (TSPP and TKPP) and the metal ions. This gum combination acts as a mediator that prevents direct harmful interactions while maintaining the beneficial chelation effects, thereby reducing metallic taste and astringency without causing phase separation.
Solution Approach 2:
The patent optimizes the concentration parameters of both the chelating agents (TSPP and TKPP at 0.25-0.75 wt% each) and the thickening gums (carboxymethyl cellulose at 0.8-1.2 wt% and xanthan gum at 0.4-0.6 wt%) to achieve a balanced formulation. By precisely controlling these parameter ranges, the composition maintains stability while effectively reducing metallic taste and astringency.
2Object-affected harmful factors
If higher concentrations of pyrophosphate compounds are used to enhance chelation effectiveness, then taste improvement is enhanced, but phase separation resistance is reduced
Solution Approach 1:
The patent establishes optimal concentration ranges for pyrophosphate compounds (0.25-0.75 wt% for each TSPP and TKPP) that balance chelation effectiveness with phase separation resistance. This parameter optimization ensures sufficient taste improvement while maintaining formulation stability under various storage conditions.
Solution Approach 2:
The patent creates a composite thickening system combining carboxymethyl cellulose and xanthan gum in specific ratios. This composite material provides enhanced synergistic effects that counterbalance the phase separation tendency of higher pyrophosphate concentrations, allowing effective chelation while maintaining reliability.
3Stability of the object's composition
If thickening gum concentration is increased to prevent phase separation, then composition stability is improved, but metallic taste and astringency may worsen
Solution Approach 1:
The patent optimizes the thickening gum concentration parameters (carboxymethyl cellulose at 0.8-1.2 wt% and xanthan gum at 0.4-0.6 wt%) to achieve sufficient phase separation resistance without excessive gum content that could interfere with chelation effectiveness and taste quality.
Solution Approach 2:
The thickening gum system acts as an intermediary that stabilizes the composition without interfering with the chelation function. The specific combination and concentrations of carboxymethyl cellulose and xanthan gum provide stability while allowing the pyrophosphate compounds to effectively reduce metallic taste and astringency.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition achieves improved phase separation stability, maintaining acceptable taste and mouthfeel, with formulations showing resistance to phase separation even under accelerated aging conditions, as demonstrated by centrifugation and real-time studies.
Implementation Method 1
Chelating agents are sometimes used in order to reduce the metallic taste and astringency of oral care compositions containing a metal ion source.
Implementation Method 2
one or more thickening gums, wherein the total concentration of thickening gums in the composition is 1.25 wt % to 1.6 wt %
Data Source
AI summary
Disclosed herein are oral care compositions comprising: a) one or more pyrophosphate compounds, wherein the total concentration of pyrophosphate compounds in the composition is 0.5 wt % to 1.5 wt %, based on the weight of the oral care composition; b) one or more thickening gums, wherein the total concentration of thickening gums in the composition is 1.25 wt % to 1.6 wt %, based on the weight of the oral care composition; and c) a metal ion source.