Oral Composition Cationic Bactericide Adsorption Stability

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Solution Overview

Problem

Conventional oral compositions containing a cationic bactericide and anionic surfactant combinations often suffer from reduced stability and solubility in the oral cavity, leading to poor adsorption of the cationic antibacterial agent on the tooth surface and inadequate biofilm formation inhibition.

Innovation Solution

An oral composition comprising olefin sulfonic acid or its salt, hydroxyalkanesulfonic acid or its salt, and a cationic bactericide, with specific carbon atom ranges and content ratios, enhancing the adsorption of the cationic bactericide on the tooth surface while maintaining stability and solubility.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-generated harmful factors

If a cationic bactericide and anionic surfactant are simply contained in combination, then the cleansing action to remove dental plaque is improved, but the stability of the oral composition and solubility in saliva are reduced

Engineering Contradiction:
Improvedental plaque removalVSAvoidcomposition stability
Core Design Contradiction:
Object-generated harmful factorsVSStability of the object's composition

Solution Approach 1:

The patent changes the chemical parameters by specifying precise carbon atom ranges (14-20) for both the anionic surfactant and hydroxy compound, and defines specific content ratios (0.01-4 mass% total surfactant, 3-50 mass% anionic surfactant in total). These parameter optimizations resolve the contradiction by achieving effective plaque removal while maintaining composition stability and solubility.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite system combining three components: anionic surfactant (for cleansing), cationic bactericide (for biofilm inhibition), and hydroxy compound (as stabilizer). This composite approach allows the components to work synergistically, where the hydroxy compound mediates between the conflicting anionic surfactant and cationic bactericide, resolving stability issues while maintaining effectiveness.

Inventive Principle:
Principle #40Composite materials

2Object-generated harmful factors

If a cationic bactericide and anionic surfactant are simply contained in combination, then the cleansing action to remove dental plaque is improved, but the adsorption of the cationic antibacterial agent on the tooth surface is poor

Engineering Contradiction:
Improvedental plaque removalVSAvoidadsorption of cationic bactericide
Core Design Contradiction:
Object-generated harmful factorsVSReliability

Solution Approach 1:

The hydroxy compound acts as an intermediary substance that mediates between the anionic surfactant and cationic bactericide. It prevents direct harmful interactions while allowing both components to function effectively, thereby improving cationic bactericide adsorption on tooth surfaces without compromising plaque removal capability.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent optimizes concentration parameters to achieve proper adsorption. By limiting total surfactant content to 0.01-4 mass% and setting anionic surfactant at 3-50 mass% of total surfactant, the formulation ensures sufficient cationic bactericide availability for tooth surface adsorption while maintaining effective cleansing action.

Inventive Principle:
Principle #35Parameter changes

3Object-generated harmful factors

If a cationic bactericide and anionic surfactant are simply contained in combination, then the cleansing action to remove dental plaque is improved, but the biofilm formation inhibitory effect is inadequate

Engineering Contradiction:
Improvedental plaque removalVSAvoidbiofilm formation inhibition
Core Design Contradiction:
Object-generated harmful factorsVSReliability

Solution Approach 1:

The patent designs a multi-functional composition where the anionic surfactant provides cleansing action, the cationic bactericide provides biofilm formation inhibition, and the hydroxy compound provides stability enhancement. This multi-functionality approach ensures both effective plaque removal and adequate biofilm inhibition without compromise.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The composite formulation combines components with complementary functions: anionic surfactant for removal, cationic bactericide for inhibition, and hydroxy compound for stability. The synergistic interaction among these components achieves both effective cleansing and reliable biofilm formation inhibition.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition achieves improved adsorption of the cationic bactericide, effective biofilm formation inhibition, comfortable foaming, and enhanced low-temperature storage stability.

Implementation Method 1

enhancing the adsorption of the cationic bactericide on the tooth surface

Methodology Applied
Scientific EffectAdsorption: Adsorption

Implementation Method 2

the solubility or the dispersibility in the saliva when applied to the oral cavity

Methodology Applied
Scientific EffectSurfactant: Surfactant

Data Source

PatentUS11123277B2Oral composition
Publication Date: 2021.09.21 KAO CORP

AI summary

The present invention relates to an oral composition which contains a cationic bactericide and an anionic surfactant in combination and is capable of enhancing the adsorption of the cationic bactericide on the tooth surface and effectively securing the composition stability and solubility or dispersity in the oral cavity. The oral composition comprises the following components (A), (B), and (C): (A) an olefin sulfonic acid having 14 or more and 20 or less carbon atoms or a salt thereof, (B) a hydroxyalkanesulfonic acid having 14 or more and 20 or less carbon atoms or a salt thereof, and (C) a cationic bactericide, wherein the total content of the component (A) and the component (B) is 0.01 mass % or more and 4 mass % or less, and the content of the component (A) is 3 mass % or more and 50 mass % or less in the total content of the component (A) and the component (B).